DOK2 抗体 (C-Term)
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- 抗原 See all DOK2 抗体
- DOK2
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, Pig, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DOK2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- QEPRGEAWRR QATRDRDPAG LQHVQPAGQD FSASGWQPGT EYDNVVLKKG
- 预测反应
- Cow: 100%, Dog: 90%, Horse: 90%, Human: 100%, Mouse: 90%, Pig: 100%, Rat: 90%
- 产品特性
- This is a rabbit polyclonal antibody against DOK2. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human DOK2
- Top Product
- Discover our top product DOK2 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 412 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- DOK2
- 别名
- DOK2 (DOK2 产品)
- 别名
- DokR antibody, Frip antibody, Dok-2 antibody, p56DOK antibody, p56dok-2 antibody, docking protein 2 antibody, DOK2 antibody, Dok2 antibody
- 背景
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DOK2 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr/abl), a chimeric protein whose presence is associated with CML. DOK2 binds p120 (RasGAP) from CML cells.The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.
Alias Symbols: p56DOK, p56dok-2
Protein Interaction Partner: UBC, RASA1, ABL1, POT1, EGFR, KIAA1279, INPP5D, NCK1, TEK, SRC, LYN, RET, LCK, IL4R, HCK, HSPA4L, ASF1B, DNAJB11, RAB10, SSSCA1, CFLAR, SPOP, SHC1, PSMD10, DOK1,
Protein Size: 412 - 分子量
- 45 kDa
- 基因ID
- 9046
- NCBI登录号
- NM_003974, NP_003965
- UniProt
- O60496
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