TRAF1 抗体 (Middle Region)
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- 抗原 See all TRAF1 抗体
- TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, Cow, 兔, 犬, 斑马鱼, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TRAF1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- DAFRPDLSSA SFQRPQSETN VASGCPLFFP LSKLQSPKHA YVKDDTMFLK
- 预测反应
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Zebrafish: 84%
- 产品特性
- This is a rabbit polyclonal antibody against TRAF1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human TRAF1
- Top Product
- Discover our top product TRAF1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 416 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))
- 别名
- TRAF1 (TRAF1 产品)
- 背景
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This protein is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins, this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors.The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins, this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: EBI6, MGC:10353
Protein Interaction Partner: ZNF662, KLHL38, TRIM42, RTP5, SSC5D, MORN3, POM121L4P, OLIG3, CCDC116, ZNF564, SLC25A48, ALS2CR11, LOC149950, ZNF417, TMC8, ZNF572, RBM45, C1orf216, ZNF440, TBC1D16, HAUS1, SYCE1, ZNF502, C5orf30, CCDC120, FBF1, ZNF587, BEX2, LCOR, FAM161A, PLEKHN1, RASSF
Protein Size: 416 - 分子量
- 46 kDa
- 基因ID
- 7185
- NCBI登录号
- NM_005658, NP_005649
- UniProt
- Q13077
- 途径
- NF-kappaB Signaling, Apoptosis, Cell-Cell Junction Organization, Asymmetric Protein Localization
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