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FFAR1 抗体 (N-Term)

FFAR1 适用: 人, 小鼠, 大鼠, Pig, 犬, Cow WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2792205
发货至: 中国
  • 抗原 See all FFAR1 抗体
    FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))
    抗原表位
    • 15
    • 10
    • 8
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    人, 小鼠, 大鼠, Pig, 犬, Cow
    宿主
    • 59
    • 1
    • 1
    克隆类型
    • 60
    • 1
    多克隆
    标记
    • 22
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FFAR1 antibody is un-conjugated
    应用范围
    • 47
    • 21
    • 13
    • 13
    • 8
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    序列
    KVSEAALSLL VLILIITSAS RSQPKVPEWV NTPSTCCLKY YEKVLPRRLV
    预测反应
    Cow: 100%, Dog: 100%, Human: 100%, Mouse: 85%, Pig: 92%, Rat: 85%
    产品特性
    This is a rabbit polyclonal antibody against FFAR1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human FFAR1
    Top Product
    Discover our top product FFAR1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 300 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Sum, Tikhonova, Neumann, Engel, Raaka, Costanzi, Gershengorn: "Identification of residues important for agonist recognition and activation in GPR40." in: The Journal of biological chemistry, Vol. 282, Issue 40, pp. 29248-55, (2007) (PubMed).

  • 抗原
    FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))
    别名
    FFAR1 (FFAR1 产品)
    别名
    FFAR1 antibody, GPR40 antibody, FFA1R antibody, GPCR40 antibody, Gpr40 antibody, free fatty acid receptor 1 antibody, FFAR1 antibody, Ffar1 antibody
    背景
    FFAR1 is receptor for medium and long chain saturated and unsaturated fatty acids. It binding of the ligand increase intracellular calcium concentration and amplify glucose-stimulated insulin secretion. The activity of this receptor is mediated by G-proteins that activate phospholipase C.
    Alias Symbols: FFA1R, GPCR40, GPR40
    Protein Interaction Partner: GNAQ, GNAI1,
    Protein Size: 300
    分子量
    31 kDa
    基因ID
    2864
    NCBI登录号
    NM_005303, NP_005294
    UniProt
    O14842
    途径
    Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Carbohydrate Homeostasis
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