CDC25A 抗体 (Middle Region)
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- 抗原 See all CDC25A 抗体
- CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, 犬, 马, 兔, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CDC25A antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- MELCEPQSYC PMHHQDHKTE LLRCRSQSKV QEGERQLREQ IALLVKDMSP
- 预测反应
- Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against CDC25A. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human CDC25A
- Top Product
- Discover our top product CDC25A Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 484 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))
- 别名
- CDC25A (CDC25A 产品)
- 别名
- cdc25a2 antibody, cdc25A antibody, sb:cb317 antibody, CDC25A2 antibody, D9Ertd393e antibody, cell division cycle 25A antibody, cell division cycle 25B antibody, cell division cycle 25A S homeolog antibody, CDC25A antibody, cdc25a antibody, cdc25b antibody, Cdc25a antibody, cdc25a.S antibody
- 背景
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CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CDC25A2
Protein Interaction Partner: ANAPC11, FZR1, FBXW11, BTRC, CUL1, SKP1, VCP, UBC, NPLOC4, YWHAQ, SCYL1, CAMK1D, POLR1D, FGF21, CHEK2, CCNI, MCM3AP, VAMP8, CUL3, XPO1, SOX5, PEX19, NFYA, NFKBIB, MTAP, SMAD3, LMO2, IL3RA, HLA-C, FTH1, EEF1A1, DMD, CHEK1, APP, TRIB3, CSNK1A1, CDK2, FAM193
Protein Size: 484 - 分子量
- 54 kDa
- 基因ID
- 993
- NCBI登录号
- NM_201567, NP_963861
- UniProt
- P30304
- 途径
- Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase
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