Cyclin D3 抗体 (C-Term)
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- 抗原 See all Cyclin D3 (CCND3) 抗体
- Cyclin D3 (CCND3)
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, Pig, 绵羊, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Cyclin D3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- CQEQIEAALR ESLREASQTS SSPAPKAPRG SSSQGPSQTS TPTDVTAIHL
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 92%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Sheep: 100%
- 产品特性
- This is a rabbit polyclonal antibody against CCND3. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human CCND3
- Top Product
- Discover our top product CCND3 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 292 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- Cyclin D3 (CCND3)
- 别名
- CCND3 (CCND3 产品)
- 别名
- zgc:103502 antibody, CCND3 antibody, 9230106B05Rik antibody, AA682053 antibody, AL024085 antibody, AW146355 antibody, C78795 antibody, cyclin D3 antibody, ccnd3 antibody, CCND3 antibody, Ccnd3 antibody
- 背景
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CCND3 encodes a protein that belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation.
Protein Interaction Partner: POLR3GL, TFIP11, CDKN1A, CDK6, CDK4, CDK5, MCM10, CDKN1B, CDK2, CDK11B, FAS, SIL1, EIF3K, ATF5, VDR, MAPK6, NME1, MYB, GC, ETV1, RBL2, POLD1, CDK14, APP, RB1, UBC, PPP1CC, PPP1CB, PPP1CA, NCOA2, MAF1, NPDC1, DMTF1, CRABP2, RARA, DTNBP1, AKAP8, EFEMP2, CAS
Protein Size: 292 - 分子量
- 33 kDa
- 基因ID
- 896
- NCBI登录号
- NM_001760, NP_001751
- UniProt
- P30281
- 途径
- Cell Division Cycle, Mitotic G1-G1/S Phases, Glycosaminoglycan Metabolic Process
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