PCNA 抗体 (C-Term)
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- 抗原 See all PCNA 抗体
- PCNA (Proliferating Cell Nuclear Antigen (PCNA))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 犬, 斑马鱼, Cow
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PCNA antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- LNFFTKATPL SSTVTLSMSA DVPLVVEYKI ADMGHLKYYL APKIEDEEGS
- 预测反应
- Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 91%
- 产品特性
- This is a rabbit polyclonal antibody against PCNA. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human PCNA
- Top Product
- Discover our top product PCNA Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 261 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Human umbilical cord mesenchymal stromal cells rescue mice from acetaminophen-induced acute liver failure." in: Cytotherapy, Vol. 16, Issue 9, pp. 1207-19, (2014) (PubMed).
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Human umbilical cord mesenchymal stromal cells rescue mice from acetaminophen-induced acute liver failure." in: Cytotherapy, Vol. 16, Issue 9, pp. 1207-19, (2014) (PubMed).
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- 抗原
- PCNA (Proliferating Cell Nuclear Antigen (PCNA))
- 别名
- PCNA (PCNA 产品)
- 别名
- PCNAR antibody, Pcna/cyclin antibody, pcna antibody, AO090003000846 antibody, 53/13 antibody, CG9193 antibody, DmPCNA antibody, Dmel\\CG9193 antibody, MUS209 antibody, Mus209 antibody, PCNA antibody, PCNA/mus209 antibody, Pcna antibody, dPCNA antibody, l(2)02448 antibody, l(2)56F antibody, l(2)56Fa antibody, l(2)s1534 antibody, cb16 antibody, fb36g03 antibody, wu:fa28e03 antibody, wu:fb36g03 antibody, pcna-A antibody, proliferating cell nuclear antigen antibody, DNA polymerase III sliding clamp antibody, Proliferating cell nuclear antigen antibody, Proliferating cell nuclear antigen-like antibody, proliferating cell nuclear antigen L homeolog antibody, proliferating cell nuclear antigen 1 antibody, PCNA antibody, Pcna antibody, pcna antibody, MMP_RS08810 antibody, ANI_1_512014 antibody, AOR_1_1500154 antibody, MGC53867 antibody, pcna.L antibody, pcna1 antibody, LOC106420145 antibody, pcn1 antibody
- 背景
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PCNA is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.
Alias Symbols: MGC8367
Protein Interaction Partner: GADD45A, CDKN1A, HUWE1, POLH, PCNA, MSH3, FUS, UBC, TMEM218, CHFR, DTL, POLE, POLD1, MCM7, MCM4, LIG1, MSH6, FEN1, FBXO18, ZRANB3, CHTF18, DNMT1, RAD18, SIVA1, KIAA0101, TDG, SUMO2, SUMO3, RPA1, RFC5, RFC4, RFC3, RFC2, RFC1, MDM2, TRIM25, USP18, ISG15, MA
Protein Size: 261 - 分子量
- 29 kDa
- 基因ID
- 5111
- NCBI登录号
- NM_002592, NP_002583
- UniProt
- P12004
- 途径
- Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagy
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