CDK6 抗体 (C-Term)
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- 抗原 See all CDK6 抗体
- CDK6 (Cyclin-Dependent Kinase 6 (CDK6))
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抗原表位
- C-Term
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适用
- 人, 小鼠, Cow, 犬, 马, 兔, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CDK6 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- LLKCLTFNPA KRISAYSALS HPYFQDLERC KENLDSHLPP SQNTSELNTA
- 预测反应
- Cow: 84%, Dog: 84%, Horse: 84%, Human: 100%, Mouse: 76%, Pig: 84%, Rabbit: 84%
- 产品特性
- This is a rabbit polyclonal antibody against CDK6. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human CDK6
- Top Product
- Discover our top product CDK6 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 326 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- CDK6 (Cyclin-Dependent Kinase 6 (CDK6))
- 别名
- CDK6 (CDK6 产品)
- 背景
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CDK6 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb.The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb.
Alias Symbols: MGC59692, PLSTIRE
Protein Interaction Partner: PSMA3, DAB1, CDKN2D, CDKN2C, CDKN2B, CCND3, UBC, CCND2, AMY2A, CDKN2A, CDK6, PIGR, DMBT1, WDR33, CDKL3, RB1, CDK4, UCHL1, PML, NUMA1, NFATC3, MYC, MLLT3, MEF2D, MCM2, ISL1, HSP90AA1, HSF1, FOXO3, FOXM1, EZH2, ELK1, DDIT3, ATF6B, CDKN1A, CDC6, CCND1, ZSCAN
Protein Size: 326 - 分子量
- 37 kDa
- 基因ID
- 1021
- NCBI登录号
- NM_001259, NP_001250
- UniProt
- Q00534
- 途径
- Cell Division Cycle, Mitotic G1-G1/S Phases
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