TIAL1 抗体 (C-Term)
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- 抗原 See all TIAL1 抗体
- TIAL1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 犬, 兔, 斑马鱼, Cow, 豚鼠, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TIAL1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- WNQQGFGVDQ SPSAAWMGGF GAQPPQGQAP PPVIPPPNQA GYGMASYQTQ
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 85%, Rabbit: 100%, Rat: 85%, Zebrafish: 76%
- 产品特性
- This is a rabbit polyclonal antibody against TIAL1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human TIAL1
- Top Product
- Discover our top product TIAL1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 375 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- TIAL1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1))
- 别名
- TIAL1 (TIAL1 产品)
- 背景
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The protein encoded by TIAL1 is a member of a family of RNA-binding proteins and possesses nucleolytic activity against cytotoxic lymphocyte target cells. The gene product is a cytotoxic granule-associated protein and has been shown to bind specifically to poly(A) homopolymers and to fragment DNA in permeabilized target cells. It has been suggested that members of this protein family may be involved in the induction of apoptosis. One isoform contains a lysosome-targeting motif in its C-terminal auxiliary domain, however, alternative splicing results in a T-cluster DNA-binding isoform, differing at the C-terminus where a hydrophobic sequence replaces the lysosome-targeting motif.
Alias Symbols: TCBP, TIAR
Protein Interaction Partner: SUMO2, UBC, RPA3, RPA2, RPA1, BMI1, SOX2, MAPK1, GADD45A, VCAM1, ITGA4, FN1, MRPL53, SARNP, UFM1, SBDS, MRPS28, TOMM40, ACAA2, GNB2L1, SF3B4, SCAMP3, SCO2, ALDH5A1, VDAC1, UBE2D2, THY1, SOD1, MBNL1, CAND1, DCUN1D1, COPS5, COPS6, CUL1, CUL2, CUL3, CUL4A, C
Protein Size: 375 - 分子量
- 42 kDa
- 基因ID
- 7073
- NCBI登录号
- NM_003252, NP_003243
- UniProt
- Q01085
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