RIPK1 抗体 (Middle Region)
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- 抗原 See all RIPK1 抗体
- RIPK1 (Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1))
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抗原表位
- Middle Region
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适用
- 人, 犬, Cow, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RIPK1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- RRRRVSHDPF AQQRPYENFQ NTEGKGTAYS SAASHGNAVH QPSGLTSQPQ
- 预测反应
- Cow: 100%, Dog: 91%, Horse: 83%, Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against RIPK1. It was validated on Western Blot using a cell lysate as a positive control.
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human RIPK1
- Top Product
- Discover our top product RIPK1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 671 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- RIPK1 (Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1))
- 别名
- RIPK1 (RIPK1 产品)
- 别名
- RIP antibody, RIP1 antibody, D330015H01Rik antibody, Rinp antibody, Rip1 antibody, rip1 antibody, ripk1 antibody, xRIP1beta antibody, xrip1 antibody, receptor interacting serine/threonine kinase 1 antibody, receptor (TNFRSF)-interacting serine-threonine kinase 1 antibody, receptor interacting serine/threonine kinase 1 L homeolog antibody, RIPK1 antibody, Ripk1 antibody, ripk1.L antibody
- 背景
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FAK overexpression in human tumors provides a survival signal function by binding to RIP and inhibiting its interaction with the death receptor complex.
Alias Symbols: RIP, RIP1
Protein Interaction Partner: RFFL, RIPK1, UBC, TRAF2, TRAF1, TNFRSF1A, TNF, OTUD1, YOD1, TRADD, IKBKG, FADD, CASP8, MAP3K7, BMH1, BIRC3, BIRC2, MAP3K8, OPTN, NUMBL, CFLAR, HSP90AA1, RIPK3, USP4, TNFAIP3, TNFSF10, LRRK2, TNFRSF10B, MAP3K3, HHV8GK18_gp80, DAB2IP, TNFRSF1B, IKBKB, CHUK,
Protein Size: 671 - 分子量
- 76 kDa
- 基因ID
- 8737
- NCBI登录号
- NM_003804, NP_003795
- UniProt
- Q13546
- 途径
- NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR signaling, Activation of Innate immune Response, Inositol Metabolic Process, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome, Ubiquitin Proteasome Pathway
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