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BAX 抗体 (N-Term)

Name: BAX 抗体 (N-Term)
SKU: ABIN2792125
Availability: OutOfStock

BAX 适用: 人, Pig, Cow, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated

WB Suggested Anti-BAX Antibody Titration: 1. (BAX 抗体 (N-Term))

Immunohistochemistry with NT2, mouse brain; rat brain. (BAX 抗体 (N-Term))

IHC

IHC

Rabbit Anti-BAX Antibody AV Paraffin Embedded Tissue: Human cardiac cell Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4. (BAX 抗体 (N-Term))

IHC

5 images

(2 references)

产品编号 ABIN2792125

发货至: 中国

Datasheet as PDF

抗原 See all BAX 抗体

BAX (BCL2-Associated X Protein (BAX))
抗原表位
36

32

18

17

15

12

11

10

9

8

8

7

6

5

4

4

3

3

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
适用
256

156

141

46

31

26

25

18

16

11

9

5

3

3

3

2

1

1

1

1

1
人, Pig, Cow, 犬
宿主
170

94

3

1
兔
Compatible Secondaries
克隆类型
184

84
多克隆
标记
134

16

13

12

10

7

5

5

5

5

5

5

5

5

5

5

5

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1
This BAX antibody is un-conjugated
应用范围
232

114

72

62

52

52

50

40

36

12

12

8

5

3

1

1

1

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

序列

MDGSGEQPRG GGPTSSEQIM KTGALLLQGF IQDRAGRMGG EAPELALDPV

预测反应

Cow: 100%, Dog: 100%, Human: 100%, Pig: 100%

产品特性

This is a rabbit polyclonal antibody against BAX. It was validated on Western Blot and immunohistochemistry.

纯化方法

Protein A purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human BAX

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anti-BCL2-Associated X Protein (BAX) (N-Term) antibody
BAX 适用: 人, 小鼠, 大鼠, 猴, Pig, Cow, 兔, 犬, 小鸡, 绵羊, 马, 豚鼠, Hamster, 山羊, Avian, Cat, 驴 WB, IF 宿主: 山羊 Polyclonal unconjugated

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BAX 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Associated X Protein (BAX) (AA 1-192) antibody
BAX 适用: 人 WB, ELISA, IF, IHC (p), PLA 宿主: 小鼠 Monoclonal 1F5-1B7 unconjugated

anti-BCL2-Associated X Protein (BAX) (AA 13-160) antibody
BAX 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 4H9B11 unconjugated

anti-BCL2-Associated X Protein (BAX) antibody
BAX 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 2D8H2 unconjugated

anti-BCL2-Associated X Protein (BAX) (AA 41-76) antibody
BAX 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB0952 unconjugated

anti-BCL2-Associated X Protein (BAX) (AA 41-76) antibody
BAX 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Associated X Protein (BAX) antibody
BAX 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 192 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
De Martino, Marfé, Longo, Fiorito, Montagnaro, Iovane, Decaro, Pagnini: "Bid cleavage, cytochrome c release and caspase activation in canine coronavirus-induced apoptosis." in: Veterinary microbiology, Vol. 141, Issue 1-2, pp. 36-45, (2010) (PubMed).

Honda, Abe, Hiroki, Honda, Iwanuma, Yanagisawa, Ide: "Activation of caspase 3, 9, 12, and Bax in masseter muscle of mdx mice during necrosis." in: Journal of muscle research and cell motility, Vol. 28, Issue 4-5, pp. 243-7, (2007) (PubMed).
抗原

BAX (BCL2-Associated X Protein (BAX))

别名

BAX (BAX 产品)

别名

BAX-ALPHA antibody, bax-A antibody, xBax antibody, xlbax antibody, BAX antibody, bax antibody, fj16e01 antibody, wu:fc50b10 antibody, wu:fj16e01 antibody, BCL2L4 antibody, zgc:112983 antibody, BCL2 associated X, apoptosis regulator antibody, BCL2-associated X protein L homeolog antibody, BCL2-associated X protein antibody, bcl2-associated X protein, a antibody, bcl2-associated X protein, b antibody, BAX antibody, bax.L antibody, bax antibody, baxa antibody, Bax antibody, baxb antibody

背景

BAX encodes a protein that belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. BAX expression is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis.
Alias Symbols: BCL2L4
Protein Interaction Partner: CYCS, ZBTB24, UBC, CASP9, CASP8, CASP7, CASP3, BCL2L1, BCL2, CLU, MDM2, MCL1, BAX, BAG3, YWHAB, VCP, CRYAB, CRYAA, BAK1, XIAP, TP53, KCNA3, HSPA4, XRCC6, XRCC5, HDAC6, BAD, PSMC5, PSMC3, PARK7, UHRF2, RNF144B, OYE2, TOMM22, TOMM40, MEPCE, MOAP1, BBC3, PPP
Protein Size: 192

分子量

21 kDa

基因ID

581

NCBI登录号

NM_138761, NP_620116

UniProt

Q07812

途径

p53 Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response