FOXO4 抗体 (Middle Region)
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- 抗原 See all FOXO4 抗体
- FOXO4 (Forkhead Box O4 (FOXO4))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, Pig, 犬, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FOXO4 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- YLYQILQGIV FCHSRRVLHR DLKPQNLLID DKGTIKLADF GLARAFGIPI
- 预测反应
- Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against FOXO4. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human FOXO4
- Top Product
- Discover our top product FOXO4 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 505 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- FOXO4 (Forkhead Box O4 (FOXO4))
- 别名
- FOXO4 (FOXO4 产品)
- 别名
- FOXO4 antibody, foxo4 antibody, AFX antibody, AFX1 antibody, MLLT7 antibody, Afxh antibody, Mllt7 antibody, afx antibody, RGD1561201 antibody, forkhead box O4 antibody, forkhead box O4 L homeolog antibody, FOXO4 antibody, foxo4.L antibody, Foxo4 antibody
- 背景
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FOXO4 is transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. The protein can down-regulate expression of HIF1A and suppress hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle. A chromosomal aberration involving FOXO4 is found in acute leukemias.
Alias Symbols: AFX, AFX1, MGC120490, MLLT7
Protein Interaction Partner: REL, SFN, AKT1, OGT, UBC, ATXN3, MDM2, NLK, USP7, CTNNB1, CREBBP, VDR, SIRT1, SMAD3, XPO1, YWHAZ, SMAD4, FOXG1, AKT2, ESR1, PIN1, CCND1, CDKN1A,
Protein Size: 505 - 分子量
- 54 kDa
- 基因ID
- 4303
- NCBI登录号
- NM_005938, NP_005929
- UniProt
- P98177
- 途径
- Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
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