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- 抗原 See all CDC42 抗体
- CDC42 (Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))
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抗原表位
- N-Term
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适用
- 犬, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CDC42 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- DNYAVTVMIG GEPYTLGLFD TAGQEDYDRL RPLSYPQTDV FLVCFSVVSP
- 预测反应
- Dog: 100%, Rabbit: 100%
- 产品特性
- This is a rabbit polyclonal antibody against CDC42. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CDC42
- Top Product
- Discover our top product CDC42 Primary Antibody
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anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) (AA 25-191) antibody
CDC42 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) antibodyCDC42 适用: 人 WB, ELISA, IHC 宿主: 兔 Monoclonal 3C3 unconjugated Recombinant Antibody
anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) (AA 1-191) antibodyCDC42 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) (AA 121-138), (Middle Region) antibodyCDC42 适用: 人, 小鼠, 大鼠, Cow WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) antibodyCDC42 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) (AA 1-188) antibodyCDC42 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) (AA 2-188) antibodyCDC42 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) antibodyCDC42 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) (AA 38-87) antibodyCDC42 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 猴, 小鸡, 兔, 非洲爪蟾, 马, Avian, 豚鼠, Insect WB 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) antibodyCDC42 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 191 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- CDC42 (Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))
- 别名
- CDC42 (CDC42 产品)
- 别名
- CDC42Hs antibody, G25K antibody, AI747189 antibody, AU018915 antibody, cdc42a antibody, wu:fb07d08 antibody, wu:fj62g06 antibody, zgc:63918 antibody, Xcdc42 antibody, cdc42hs antibody, g25k antibody, CDC42 antibody, CG12530 antibody, Cdc42Dm antibody, D-CDC42 antibody, D-Cdc42 antibody, D-cdc42 antibody, DCDC42 antibody, DCdc42 antibody, Dcdc42 antibody, Dm Cdc42 antibody, DmCDC42 antibody, Dmcdc42 antibody, Dmel\\CG12530 antibody, cdc42 antibody, cell division cycle 42 antibody, Cell division control protein 42 homolog antibody, cell division control protein 42 homolog antibody, cell division cycle 42 L homeolog antibody, CG12530 gene product from transcript CG12530-RC antibody, Rho family GTPase antibody, CDC42 antibody, Cdc42 antibody, cdc42 antibody, LOC100636735 antibody, LOC100637699 antibody, LOC100638834 antibody, cdc42.L antibody
- 背景
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CDC42 is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants.The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants.
Alias Symbols: CDC42Hs, G25K
Protein Interaction Partner: PARD6B, CDC42EP1, CDC42EP2, PAK2, UBC, TRAF2, PAK1, ARHGDIA, BIRC2, TNK2, TCEB2, EPRS, LARS, RUVBL1, NEK6, WIPF1, WASL, RIOK3, SSX2IP, DIAPH3, BAIAP2, PAK3, ZNF420, IQGAP1, RAP1A, WAS, TGFBR2, TGFBR1, ARHGEF6, LRRK2, FGD3, ARHGAP1, SH3RF3, BCAR1, USP6, EL
Protein Size: 191 - 分子量
- 21 kDa
- 基因ID
- 998
- NCBI登录号
- NM_001791, NP_001782
- UniProt
- P60953
- 途径
- MAPK Pathway, Microtubule Dynamics, RTK signaling, WNT signaling, TCR Signaling, EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Signaling Events mediated by VEGFR1 and VEGFR2, EGFR Downregulation, VEGF Signaling
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