The protein encoded by this gene is a nuclear import receptor for serine/arginine-rich (SR) proteins such as the splicing factors SFRS1 and SFRS2. The encoded protein has also been shown to be involved in HIV-1 infection, apparently through interaction with the HIV-1 capsid protein. Two transcript variants encoding different isoforms as well as a noncoding transcript have been found for this gene. Protein Interaction Partner: UBC, SUMO1, NEDD8, ELAC2, IPO9, TTLL12, PFDN6, ARPC2, ACTR3, PPP3CA, PPP2R1A, PPP2CA, HNRNPH1, FEN1, ALDOA, CLK3, CLK2, EGFR, SOX2, SMURF2, CFTR, VCP, CA9, UBE3A, TNPO1, CHMP3, ELAVL1, USP19, TRA2B, SRSF1, C20orf24, BRF2, PHLDA3, Protein Size: 859