MVB12B 抗体 (C-Term)
MVB12B
适用: 人, 小鼠, 大鼠, 豚鼠, 兔, Cow, 犬, 马
WB
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all MVB12B 抗体
- MVB12B (Multivesicular Body Subunit 12B (MVB12B))
- 抗原表位
- C-Term
- 适用
- 人, 小鼠, 大鼠, 豚鼠, 兔, Cow, 犬, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MVB12B antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- HISLTLPATF RGRNSTRTDY EYQHSNLYAI SAMDGVPFMI SEKFSCVPES
- 预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 85%, Rabbit: 93%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against MVB12B. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human MVB12B
- Top Product
- Discover our top product MVB12B Primary Antibody
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeat freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- MVB12B (Multivesicular Body Subunit 12B (MVB12B))
- 别名
- MVB12B (MVB12B 产品)
- 背景
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The protein encoded by this gene is a component of the ESCRT-I complex, a heterotetramer, which mediates the sorting of ubiquitinated cargo protein from the plasma membrane to the endosomal vesicle. ESCRT-I complex plays an essential role in HIV budding and endosomal protein sorting. Depletion and overexpression of this and related protein (MVB12A) inhibit HIV-1 infectivity and induce unusual viral assembly defects, indicating a role for MVB12 subunits in regulating ESCRT-mediated virus budding. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: C9orf28, MVB12B
Protein Interaction Partner: LNX1, gag, UBC, VPS37A, MVB12A, TSG101,
Protein Size: 319 - 分子量
- 35 kDa
- 基因ID
- 89853
- NCBI登录号
- NM_033446, NP_258257
- UniProt
- Q9H7P6
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