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- 抗原 See all PLD6 抗体
- PLD6 (Phospholipase D Family, Member 6 (PLD6))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PLD6 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- ITEDDEYVRL FLEEFERIWE QFNPTKYTFF PPKKSHGSCA PPVSRAGGRL
- 预测反应
- Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against PLD6. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human PLD6
- Top Product
- Discover our top product PLD6 Primary Antibody
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anti-Phospholipase D Family, Member 6 (PLD6) (AA 1-252) antibody
PLD6 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Phospholipase D Family, Member 6 (PLD6) (AA 125-154) antibodyPLD6 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB28958 unconjugated
anti-Phospholipase D Family, Member 6 (PLD6) (AA 125-154) antibodyPLD6 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 252 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PLD6 (Phospholipase D Family, Member 6 (PLD6))
- 别名
- PLD6 (PLD6 产品)
- 别名
- ZUC antibody, 4933433K01Rik antibody, Gm10 antibody, Zuc antibody, mZuc antibody, mitoPLD antibody, pld6 antibody, fc55d08 antibody, wu:fc55d08 antibody, phospholipase D family member 6 antibody, phospholipase D family, member 6 antibody, phospholipase D family member 6 S homeolog antibody, PLD6 antibody, Pld6 antibody, pld6.S antibody, pld6 antibody
- 背景
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PLD6 is a cardiolipin hydrolase present at the mitochondrial outer membrane required both for mitochondrial fusion and piRNA metabolic process. PLD6 acts by catalyzing the hydrolysis of cardiolipin (diphosphatidylglycerol) to form phosphatidate (phosphatidic acid or PA) at the mitochondrial outer membrane surface, promoting mitochondrial fusion. The production of phosphatidate also regulates the piRNA metabolic process by promoting recruitment and/or activation of components of the meiotic nuage, also named P granule, a critical step for primary biogenesis of piRNAs. It is required during spermatogenesis to repress transposable elements and prevent their mobilization via its role in the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons.
Alias Symbols: -
Protein Interaction Partner: ELAVL1, UBC,
Protein Size: 252 - 分子量
- 28 kDa
- 基因ID
- 201164
- NCBI登录号
- NM_178836, NP_849158
- UniProt
- Q8N2A8
- 途径
- Ribonucleoprotein Complex Subunit Organization
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