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- 抗原 See all C1orf86 (C1ORF86) products
- C1orf86 (C1ORF86) (Chromosome 1 Open Reading Frame 86 (C1ORF86))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This C1orf86 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- ARSLPQRPAP DPCRAPRVEQ QPSVEGAAAL RSCPMCQKEF APRLTQLDVD
- 预测反应
- Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against C1orf86. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human C1orf86
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 180 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- C1orf86 (C1ORF86) (Chromosome 1 Open Reading Frame 86 (C1ORF86))
- 别名
- C1orf86 (C1ORF86 产品)
- 别名
- FAAP20 antibody, FP7162 antibody, Fanconi anemia core complex associated protein 20 antibody, FAAP20 antibody
- 背景
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C1orf86 is a component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. It promotes translesion synthesis via interaction with REV1.
Alias Symbols: FP7162
Protein Interaction Partner: FANCL, FANCA, UBC, FANCC, APITD1, C19orf40, C17orf70, FANCM, REV1, FANCG, FANCF, FANCB, FANCE, ELAVL1,
Protein Size: 180 - 分子量
- 19 kDa
- 基因ID
- 199990
- NCBI登录号
- NM_182533, NP_872339
- UniProt
- Q6NZ36
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