电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

MACROD1 抗体 (N-Term)

MACROD1 适用: 人, Cow, 犬, 豚鼠, 马, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2791083
发货至: 中国
  • 抗原 See all MACROD1 products
    MACROD1 (MACRO Domain Containing 1 (MACROD1))
    抗原表位
    • 5
    • 1
    N-Term
    适用
    人, Cow, 犬, 豚鼠, 马, 小鼠, 大鼠
    宿主
    • 6
    克隆类型
    • 6
    多克隆
    标记
    • 2
    • 2
    • 1
    • 1
    This MACROD1 antibody is un-conjugated
    应用范围
    • 4
    • 1
    • 1
    Western Blotting (WB)
    序列
    MAAKVDLSTS TDWKEAKSFL KGLSDKQREE HYFCKDFVRL KKIPTWKEMA
    预测反应
    Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against MACROD1. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N-terminal region of Human MACROD1
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 325 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    MACROD1 (MACRO Domain Containing 1 (MACROD1))
    别名
    MACROD1 (MACROD1 产品)
    别名
    lrp16 antibody, d930010j01rik antibody, LRP16 antibody, AI604841 antibody, AW743046 antibody, D930010J01Rik antibody, Lrp16 antibody, MACRO domain containing 1 antibody, MACRO domain containing 1 L homeolog antibody, MACROD1 antibody, macrod1 antibody, macrod1.L antibody, Macrod1 antibody
    背景
    MACROD1 deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins. It plays a role in estrogen signaling. Binds to androgen receptor (AR) and amplifies the transactivation function of AR in response to androgen and may play an important role in carcinogenesis and/or progression of hormone-dependent cancers by feed-forward mechanism that activates ESR1 transactivation. It could be an ESR1 coactivator, providing a positive feedback regulatory loop for ESR1 signal transduction and could be involved in invasive growth by down-regulating CDH1 in endometrial cancer cells. MACROD1 enhances ESR1-mediated transcription activity.
    Alias Symbols: LRP16
    Protein Interaction Partner: BAG3, EPB41,
    Protein Size: 325
    分子量
    36 kDa
    基因ID
    28992
    NCBI登录号
    NM_014067, NP_054786
    UniProt
    Q9BQ69
You are here:
客服