MACROD1 抗体 (N-Term)
MACROD1
适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马
WB
宿主: 兔
Polyclonal
unconjugated
1 image
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- 抗原 See all MACROD1 products
- MACROD1 (MACRO Domain Containing 1 (MACROD1))
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抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MACROD1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- MAAKVDLSTS TDWKEAKSFL KGLSDKQREE HYFCKDFVRL KKIPTWKEMA
- 预测反应
- Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against MACROD1. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human MACROD1
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anti-MACRO Domain Containing 1 (MACROD1) (AA 83-325) antibody
MACROD1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-MACRO Domain Containing 1 (MACROD1) (AA 83-132) antibodyMACROD1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 325 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- MACROD1 (MACRO Domain Containing 1 (MACROD1))
- 别名
- MACROD1 (MACROD1 产品)
- 别名
- lrp16 antibody, d930010j01rik antibody, LRP16 antibody, AI604841 antibody, AW743046 antibody, D930010J01Rik antibody, Lrp16 antibody, MACRO domain containing 1 antibody, MACRO domain containing 1 L homeolog antibody, MACROD1 antibody, macrod1 antibody, macrod1.L antibody, Macrod1 antibody
- 背景
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MACROD1 deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins. It plays a role in estrogen signaling. Binds to androgen receptor (AR) and amplifies the transactivation function of AR in response to androgen and may play an important role in carcinogenesis and/or progression of hormone-dependent cancers by feed-forward mechanism that activates ESR1 transactivation. It could be an ESR1 coactivator, providing a positive feedback regulatory loop for ESR1 signal transduction and could be involved in invasive growth by down-regulating CDH1 in endometrial cancer cells. MACROD1 enhances ESR1-mediated transcription activity.
Alias Symbols: LRP16
Protein Interaction Partner: BAG3, EPB41,
Protein Size: 325 - 分子量
- 36 kDa
- 基因ID
- 28992
- NCBI登录号
- NM_014067, NP_054786
- UniProt
- Q9BQ69
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