EFTUD1 抗体 (N-Term)
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- 抗原 See all EFTUD1 抗体
- EFTUD1 (Elongation Factor Tu GTP Binding Domain Containing 1 (EFTUD1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EFTUD1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- KVLEERAERE TESQVNPNSE QGEQVYDWST GLEDTDDSHL YFSPEQGNVV
- 预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 79%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against EFTUD1. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human EFTUD1
- Top Product
- Discover our top product EFTUD1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 1069 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- EFTUD1 (Elongation Factor Tu GTP Binding Domain Containing 1 (EFTUD1))
- 别名
- EFTUD1 (EFTUD1 产品)
- 别名
- FAM42A antibody, HsT19294 antibody, RIA1 antibody, 4932434J20Rik antibody, 6030468D11Rik antibody, AI451340 antibody, AU019507 antibody, AU022896 antibody, D7Ertd791e antibody, elongation factor like GTPase 1 antibody, elongation factor like GPTase 1 antibody, EFL1 antibody, Efl1 antibody
- 背景
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EFTUD1 is involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with SBDS, EFTUD1 triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. EFTUD1 has low intrinsic GTPase activity. GTPase activity is increased by contact with 60S ribosome subunits.
Alias Symbols: FAM42A, HsT19294, RIA1
Protein Interaction Partner: TP53RK, FKBP10, RPRD1B, OSGEP, PANK4, NSUN2, UFM1, KIAA1279, ACTR2, TPD52L2, RANGAP1, LPP, BAG1, UBC,
Protein Size: 1069 - 分子量
- 117 kDa
- 基因ID
- 79631
- NCBI登录号
- NM_001040610, NP_001035700
- 途径
- Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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