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- 抗原 See all DENND1C 抗体
- DENND1C (DENN/MADD Domain Containing 1C (DENND1C))
- 抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DENND1C antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- PSSLEDPRAR PPKALLAERA HLQPREEPGA LNSPATPTSN CQKSQPSSRP
- 预测反应
- Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against DENND1C. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human DENND1C
- Top Product
- Discover our top product DENND1C Primary Antibody
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anti-DENN/MADD Domain Containing 1C (DENND1C) (AA 601-801) antibody
DENND1C 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 801 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- DENND1C (DENN/MADD Domain Containing 1C (DENND1C))
- 别名
- DENND1C (DENND1C 产品)
- 别名
- FAM31C antibody, 4432409M07Rik antibody, DENN/MADD domain containing 1C L homeolog antibody, DENN/MADD domain containing 1C antibody, DENN domain containing 1C antibody, dennd1c.L antibody, DENND1C antibody, Dennd1c antibody
- 背景
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Clathrin-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1C, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 and bind to clathrin and clathrin adaptor protein-2. Thus, connecdenns link RAB35 activation with the clathrin machinery.
Alias Symbols: FAM31C
Protein Interaction Partner: APP, ELAVL1,
Protein Size: 801 - 分子量
- 87 kDa
- 基因ID
- 79958
- NCBI登录号
- NM_024898, NP_079174
- UniProt
- Q8IV53
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