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SPAG1 抗体 (N-Term)

SPAG1 适用: 人, 犬 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2790231
发货至: 中国
  • 抗原 See all SPAG1 抗体
    SPAG1 (Sperm Associated Antigen 1 (SPAG1))
    抗原表位
    • 10
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 29
    • 1
    • 1
    人, 犬
    宿主
    • 28
    • 1
    克隆类型
    • 29
    多克隆
    标记
    • 12
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SPAG1 antibody is un-conjugated
    应用范围
    • 21
    • 16
    • 16
    • 2
    • 1
    Western Blotting (WB)
    序列
    LHVGKEKYSK RPTKKKTPRD YAEWDKFDVE KECLKIDEDY KEKTVIDKSH
    预测反应
    Dog: 85%, Human: 100%
    产品特性
    This is a rabbit polyclonal antibody against SPAG1. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N-terminal region of human SPAG1
    Top Product
    Discover our top product SPAG1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeat freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    SPAG1 (Sperm Associated Antigen 1 (SPAG1))
    别名
    SPAG1 (SPAG1 产品)
    别名
    cb1089 antibody, MGC162178 antibody, wu:fj78g10 antibody, sp75 antibody, tpis antibody, hsd-3.8 antibody, HSD-3.8 antibody, SP75 antibody, TPIS antibody, sperm associated antigen 1 antibody, sperm associated antigen 1a antibody, SPAG1 antibody, spag1a antibody, CpipJ_CPIJ006297 antibody, spag1 antibody, Spag1 antibody
    背景
    The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm agglutinating antibodies from an infertile woman. Furthermore, immunization of female rats with the recombinant human protein reduced fertility. This protein localizes to the plasma membrane of germ cells in the testis and to the post-acrosomal plasma membrane of mature spermatozoa. Recombinant polypeptide binds GTP and exhibits GTPase activity. Thus, this protein may regulate GTP signal transduction pathways involved in spermatogenesis and fertilization. Two transcript variants of this gene encode the same protein.
    Alias Symbols: SP75, TPIS, CT140, CILD28, HSD-3.8, HEL-S-268
    Protein Size: 416
    分子量
    45 kDa
    基因ID
    6674
    NCBI登录号
    NM_003114, NP_003105
    UniProt
    G3XAM3
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