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- 抗原 See all SPAG1 抗体
- SPAG1 (Sperm Associated Antigen 1 (SPAG1))
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抗原表位
- N-Term
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适用
- 人, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SPAG1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- LHVGKEKYSK RPTKKKTPRD YAEWDKFDVE KECLKIDEDY KEKTVIDKSH
- 预测反应
- Dog: 85%, Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against SPAG1. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of human SPAG1
- Top Product
- Discover our top product SPAG1 Primary Antibody
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anti-Sperm Associated Antigen 1 (SPAG1) (AA 1-365) antibody
SPAG1 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sperm Associated Antigen 1 (SPAG1) antibodySPAG1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sperm Associated Antigen 1 (SPAG1) antibodySPAG1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sperm Associated Antigen 1 (SPAG1) (AA 175-283) antibodySPAG1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Sperm Associated Antigen 1 (SPAG1) (AA 124-152), (N-Term) antibodySPAG1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB24228 unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeat freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- SPAG1 (Sperm Associated Antigen 1 (SPAG1))
- 别名
- SPAG1 (SPAG1 产品)
- 别名
- cb1089 antibody, MGC162178 antibody, wu:fj78g10 antibody, sp75 antibody, tpis antibody, hsd-3.8 antibody, HSD-3.8 antibody, SP75 antibody, TPIS antibody, sperm associated antigen 1 antibody, sperm associated antigen 1a antibody, SPAG1 antibody, spag1a antibody, CpipJ_CPIJ006297 antibody, spag1 antibody, Spag1 antibody
- 背景
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The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm agglutinating antibodies from an infertile woman. Furthermore, immunization of female rats with the recombinant human protein reduced fertility. This protein localizes to the plasma membrane of germ cells in the testis and to the post-acrosomal plasma membrane of mature spermatozoa. Recombinant polypeptide binds GTP and exhibits GTPase activity. Thus, this protein may regulate GTP signal transduction pathways involved in spermatogenesis and fertilization. Two transcript variants of this gene encode the same protein.
Alias Symbols: SP75, TPIS, CT140, CILD28, HSD-3.8, HEL-S-268
Protein Size: 416 - 分子量
- 45 kDa
- 基因ID
- 6674
- NCBI登录号
- NM_003114, NP_003105
- UniProt
- G3XAM3
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