SELPLG 抗体 (C-Term)
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- 抗原 See all SELPLG 抗体
- SELPLG (Selectin P Ligand (SELPLG))
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抗原表位
- C-Term
- 适用
- 人, 大鼠, Cow, 犬, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SELPLG antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- EMVCISSLLP DGGEGPSATA NGGLSKAKSP GLTPEPREDR EGDDLTLHSF
- 预测反应
- Cow: 91%, Dog: 83%, Guinea Pig: 92%, Human: 100%, Rat: 83%
- 产品特性
- This is a rabbit polyclonal antibody against SELPLG. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human SELPLG
- Top Product
- Discover our top product SELPLG Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 412 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- SELPLG (Selectin P Ligand (SELPLG))
- 别名
- SELPLG (SELPLG 产品)
- 别名
- CD162 antibody, CLA antibody, PSGL-1 antibody, PSGL1 antibody, SELPLG antibody, SELPG antibody, Psgl-1 antibody, Psgl1 antibody, Selp1 antibody, Selpl antibody, selectin P ligand antibody, selectin, platelet (p-selectin) ligand antibody, clasper antibody, SELPLG antibody, Selplg antibody, cla antibody
- 背景
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This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.
Alias Symbols: CD162, CLA, PSGL-1, PSGL1
Protein Interaction Partner: MAGEA1, TNIP1, PIK3R1, GALNT4, BACE1, TPST2, TPST1, SELL, SYK, MSN, SELP, SELE, VCAN, CTSG, SELPLG,
Protein Size: 412 - 分子量
- 39 kDa
- 基因ID
- 6404
- NCBI登录号
- NM_003006, NP_002997
- UniProt
- Q14242
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