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DEF6 抗体 (C-Term)
DEF6
适用: 人, 小鼠, 大鼠, 犬, Pig, Cow, 马, 兔, 豚鼠
WB
宿主: 兔
Polyclonal
unconjugated
DEF6抗体详情
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抗原
See all DEF6 抗体
DEF6
(Differentially Expressed in FDCP 6 Homolog (DEF6))
抗原表位
All epitopes for DEF6 抗体
C-Term
适用
All reactivities for DEF6 抗体
人, 小鼠, 大鼠, 犬, Pig, Cow, 马, 兔, 豚鼠
宿主
All hosts for DEF6 抗体
兔
克隆类型
All clonalities for DEF6 抗体
多克隆
标记
All conjugates for DEF6 抗体
This DEF6 antibody is un-conjugated
应用范围
All applications for DEF6 抗体
Western Blotting (WB)
序列
QERYIERAQQ EKEELQQEMA QQSRSLQQAQ QQLEEVRQNR QRADEDVEAA
预测反应
Cow: 93%, Dog: 93%, Guinea Pig: 83%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 90%, Rabbit: 93%, Rat: 93%
产品特性
This is a rabbit polyclonal antibody against DEF6. It was validated on Western Blot.
纯化方法
Affinity Purified
免疫原
The immunogen is a synthetic peptide directed towards the C-terminal region of human BRCC3
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Discover our top product DEF6 Primary Antibody
Alternatives
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使用细节
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限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
1 mg/mL
缓冲液
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeat freeze-thaw cycles.
储存条件
-20 °C
储存方法
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
DEF6目标详情
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抗原
DEF6
(Differentially Expressed in FDCP 6 Homolog (DEF6))
别名
DEF6 (DEF6 产品 )
别名
DEF6 antibody, Def6 antibody, zgc:63721 antibody, ibp antibody, slat antibody, swap70l antibody, MGC68775 antibody, 2410003F05Rik antibody, 6430538D02Rik antibody, AV094905 antibody, Ibp antibody, Slat antibody, Slat2 antibody, Slat6 antibody, IBP antibody, SLAT antibody, SWAP70L antibody, DEF6, guanine nucleotide exchange factor antibody, differentially expressed in FDCP 6a homolog (mouse) antibody, DEF6, guanine nucleotide exchange factor L homeolog antibody, differentially expressed in FDCP 6 antibody, DEF6 guanine nucleotide exchange factor antibody, DEF6 antibody, def6a antibody, def6.L antibody, def6 antibody, Def6 antibody
背景
This gene encodes a subunit of the BRCA1-BRCA2-containing complex (BRCC), which is an E3 ubiquitin ligase. This complex plays a role in the DNA damage response, where it is responsible for the stable accumulation of BRCA1 at DNA break sites. The component encoded by this gene can specifically cleave Lys 63-linked polyubiquitin chains, and it regulates the abundance of these polyubiquitin chains in chromatin. The loss of this gene results in abnormal angiogenesis and is associated with syndromic moyamoya, a cerebrovascular angiopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 5. Alias Symbols: C6.1A, BRCC36, CXorf53 Protein Size: 376
分子量
41 kDa
基因ID
79184
NCBI登录号
NM_001018055 , NP_001018065
UniProt
P46736
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