CILP 抗体 (C-Term)
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- 抗原 See all CILP 抗体
- CILP (Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP))
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抗原表位
- C-Term
- 适用
- 人, 大鼠, 小鼠, 犬, 马, Pig, 兔, Cow
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CILP antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- YIKVKIVGPL EVNVRSRNMG GTHRQTVGKL YGIRDVRSTR DRDQPNVSAA
- 预测反应
- Cow: 86%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against CILP. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product CILP Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 1184 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- CILP (Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP))
- 别名
- CILP (CILP 产品)
- 别名
- CILP-1 antibody, HsT18872 antibody, 9830114D16 antibody, C130036G17Rik antibody, NTPPH antibody, CILP antibody, im:7137994 antibody, cartilage intermediate layer protein antibody, cartilage intermediate layer protein, nucleotide pyrophosphohydrolase antibody, cartilage intermediate layer protein 1 antibody, CILP antibody, Cilp antibody, cilp antibody, LOC100336614 antibody
- 背景
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Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. This gene encodes the cartilage intermediate layer protein (CILP), which increases in early osteoarthrosis cartilage. The encoded protein was thought to encode a protein precursor for two different proteins, an N-terminal CILP and a C-terminal homolog of NTPPHase, however, later studies identified no nucleotide pyrophosphatase phosphodiesterase (NPP) activity. The full-length and the N-terminal domain of this protein was shown to function as an IGF-1 antagonist. An allelic variant of this gene has been associated with lumbar disc disease.
Alias Symbols: CILP-1, HsT18872
Protein Interaction Partner: NEDD1, CDC20,
Protein Size: 1184 - 分子量
- 52 kDa
- 基因ID
- 8483
- NCBI登录号
- NM_003613, NP_003604
- UniProt
- O75339
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