PANK2 抗体 (C-Term)
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- 抗原 See all PANK2 抗体
- PANK2 (Pantothenate Kinase 2 (PANK2))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, 兔, 斑马鱼, 绵羊, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PANK2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- ERFGLPGWAV ASSFGNMMSK EKREAVSKED LARATLITIT NNIGSIARMC
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 86%
- 产品特性
- This is a rabbit polyclonal antibody against PANK2. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product PANK2 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 570 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PANK2 (Pantothenate Kinase 2 (PANK2))
- 别名
- PANK2 (PANK2 产品)
- 别名
- ATPANK2 antibody, F10M6.180 antibody, F10M6_180 antibody, pantothenate kinase 2 antibody, PANK2 antibody, C20orf48 antibody, HARP antibody, HSS antibody, NBIA1 antibody, PKAN antibody, 4933409I19Rik antibody, AI642621 antibody, pantothenate kinase 2 antibody, pantothenate kinase 2, mitochondrial antibody, ribonuclease A family member 11 (inactive) antibody, PANK2 antibody, Tsp_01576 antibody, LOC100539295 antibody, Pank2 antibody, RNASE11 antibody
- 背景
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This gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms.
Alias Symbols: C20orf48, FLJ17232, HARP, HSS, MGC15053, NBIA1, PKAN
Protein Interaction Partner: UBC, DHX36, QRICH2, LXN, YWHAQ, VDAC1, RASGRF2,
Protein Size: 570 - 分子量
- 47 kDa
- 基因ID
- 80025
- NCBI登录号
- NM_153638, NP_705902
- UniProt
- Q9BZ23
- 途径
- Ribonucleoside Biosynthetic Process
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