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Transferrin Receptor 抗体 (N-Term)

TFRC 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN971870
发货至: 中国
  • 抗原 See all Transferrin Receptor (TFRC) 抗体
    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
    抗原表位
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    N-Term
    适用
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    宿主
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    克隆类型
    • 156
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    多克隆
    标记
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    This Transferrin Receptor antibody is un-conjugated
    应用范围
    • 145
    • 135
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    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    GYLGYCKGVE PKTECERLAG TESPVREEPG EDFPAARRLY WDDLKRKLSE
    预测反应
    Human: 100%
    产品特性
    This is a rabbit polyclonal antibody against TFRC. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    Top Product
    Discover our top product TFRC Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 760 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
    别名
    TFRC (TFRC 产品)
    背景
    TFRC is a cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system By similarity. A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.
    Alias Symbols: CD71, TFR, TFR1, TRFR, T9, TR, p90
    Protein Interaction Partner: HUWE1, UBC, SGTA, CAV1, TP53, RAB8A, RANBP9, LGR4, MDM2, RPA3, RPA2, RPA1, ASB4, RNF2, OPTN, ADRB2, CLN3, MARCH8, env, MARCH1, MYO1G, VCAM1, ITGA4, FN1, ATF2, B4GALT1, ESR1, ATP6V1B1, FBXO6, KCNA5, KCNA3, vpu, SH3BP4, PARK2, LAPTM4B, LAPTM4A, HGS, SUMO2,
    Protein Size: 760
    分子量
    84 kDa
    基因ID
    7037
    NCBI登录号
    NM_003234, NP_003225
    UniProt
    P02786
    途径
    Transition Metal Ion Homeostasis
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