PDE6B 抗体 (N-Term)
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- 抗原 See all PDE6B 抗体
- PDE6B (phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠, 兔, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PDE6B antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- LSMPIVNKKE EIVGVATFYN RKDGKPFDEQ DEVLMESLTQ FLGWSVMNTD
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
- 产品特性
- This is a rabbit polyclonal antibody against PDE6B. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product PDE6B Primary Antibody
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anti-phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B) (AA 1-190) antibody
PDE6B 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B) antibodyPDE6B 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B) (AA 105-154) antibodyPDE6B 适用: 人, Cow, 犬, 马, 豚鼠, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B) (AA 1-853) antibodyPDE6B 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B) (AA 372-421) antibodyPDE6B 适用: 人, Cow, 犬, 马 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 575 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PDE6B (phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B))
- 别名
- PDE6B (PDE6B 产品)
- 别名
- CSNB3 antibody, CSNBAD2 antibody, PDEB antibody, RP40 antibody, rd1 antibody, PDBS antibody, RCD-1 antibody, Pdeb antibody, r antibody, rd antibody, rd-1 antibody, rd10 antibody, phosphodiesterase 6B antibody, phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide antibody, PDE6B antibody, Pde6b antibody
- 背景
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Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CSNB3, CSNBAD2, PDEB, RP40, rd1
Protein Interaction Partner: PPP1CC,
Protein Size: 575 - 分子量
- 63 kDa
- 基因ID
- 5158
- NCBI登录号
- NM_001145292, NP_001138764
- UniProt
- E7ETT3
- 途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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