Neural Wiskott-Aldrich syndrome protein (WASL) (Middle Region) 抗体
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- 抗原 See all Neural Wiskott-Aldrich syndrome protein (WASL) 抗体
- Neural Wiskott-Aldrich syndrome protein (WASL)
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, 马, Pig, 兔, Cow, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- 非结合性
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- ISHTKEKKKG KAKKKRLTKA DIGTPSNFQH IGHVGWDPNT GFDLNNLDPE
- 预测反应
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against WASL. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product WASL Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 505 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- Neural Wiskott-Aldrich syndrome protein (WASL)
- 别名
- WASL (WASL 产品)
- 别名
- N-WASP antibody, TRS4 antibody, NWASP antibody, WASPB antibody, 2900021I12Rik antibody, 3110031I02Rik antibody, zgc:158395 antibody, n-wasp antibody, nwasp antibody, wasl antibody, zgc:55478 antibody, zgc:77237 antibody, Wiskott-Aldrich syndrome-like antibody, Wiskott-Aldrich syndrome like antibody, Wiskott-Aldrich syndrome-like (human) antibody, Wiskott-Aldrich syndrome-like a antibody, Wiskott-Aldrich syndrome like L homeolog antibody, Wiskott-Aldrich syndrome-like b antibody, Wasl antibody, WASL antibody, wasla antibody, wasl.L antibody, waslb antibody
- 背景
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The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. The WASL gene product is a homolog of WAS protein, however, unlike the latter, it is ubiquitously expressed and shows highest expression in neural tissues. It has been shown to bind Cdc42 directly, and induce formation of long actin microspikes.
Alias Symbols: DKFZp779G0847, MGC48327, N-WASP, NWASP
Protein Interaction Partner: RHOJ, ARPC3, RNF8, NCK2, WIPF1, SDCBP, PTK6, GRB2, IQGAP1, WWOX, SNX9, APBB1, PRPF40A, FNBP1L, FNBP1, TRIP10, PSTPIP1, ACTG1, SORBS3, ACTR2, ACTR3, LCK, CDC42, RPL7AP66, ZNF395, BAIAP2, ARPC1B, FCHSD2, IPO5, HP, HSP90AB1, HSP90AA1, SRC, WASF2, APP, WIPF2,
Protein Size: 505 - 分子量
- 56 kDa
- 基因ID
- 8976
- NCBI登录号
- NM_003941, NP_003932
- UniProt
- O00401
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