SOCS2 抗体 (C-Term)
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- 抗原 See all SOCS2 抗体
- SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))
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抗原表位
- C-Term
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适用
- 人, 大鼠, 小鼠, Pig, Cow, 犬, 兔, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SOCS2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- KQFDSVVHLI DYYVQMCKDK RTGPEAPRNG TVHLYLTKPL YTSAPSLQHL
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against SOCS2. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product SOCS2 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 198 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))
- 别名
- SOCS2 (SOCS2 产品)
- 别名
- CIS2 antibody, Cish2 antibody, SOCS-2 antibody, SSI-2 antibody, SSI2 antibody, STATI2 antibody, Cish1 antibody, Socs-1 antibody, Socs-2 antibody, si:dkey-202b22.1 antibody, socs2 antibody, cis2 antibody, ssi2 antibody, cish2 antibody, ssi-2 antibody, socs-2 antibody, stati2 antibody, 8030460M17 antibody, AI527257 antibody, AW108012 antibody, D130043N08Rik antibody, JAB antibody, hg antibody, Cradd antibody, Socs2 antibody, suppressor of cytokine signaling 2 antibody, suppressor of cytokine signaling 1 antibody, death domain-containing protein CRADD antibody, suppressor of cytokine signaling 2 S homeolog antibody, SOCS2 antibody, Socs1 antibody, Socs2 antibody, socs2 antibody, LOC100716104 antibody, socs2.S antibody
- 背景
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This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10 and interferon (IFN)-gamma. The protein encoded by this gene is found to interact with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R), and thus is thought to be involved in the regulation of IGF1R mediated cell signaling. Knockout studies in mice also suggested a regulatory role of this gene in IGF-1 related growth control.
Alias Symbols: CIS2, Cish2, SOCS-2, SSI-2, SSI2, STATI2
Protein Interaction Partner: Tceb1, CUL5, UBC, FLT3, ARFIP2, TPD52, PLA2G1B, BMI1, SOCS3, LCK, GHR, CCNC, RYBP, PTK2B, RNF7, TCEB2, EPOR, PTK2, PRLR, INSR, IGF1R, SOCS1,
Protein Size: 198 - 分子量
- 22 kDa
- 基因ID
- 8835
- NCBI登录号
- NM_003877, NP_003868
- UniProt
- O14508
- 途径
- JAK/STAT Signaling, Response to Growth Hormone Stimulus
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