GTPase NRas 抗体 (Middle Region)
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- 抗原 See all GTPase NRas (NRAS) 抗体
- GTPase NRas (NRAS)
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抗原表位
- Middle Region
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适用
- 人, 大鼠, 小鼠, 犬, Cow, 马, 豚鼠, 兔, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GTPase NRas antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- ADINLYREQI KRVKDSDDVP MVLVGNKCDL PTRTVDTKQA HELAKSYGIP
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
- 产品特性
- This is a rabbit polyclonal antibody against NRAS. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product NRAS Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 189 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- GTPase NRas (NRAS)
- 别名
- NRAS (NRAS 产品)
- 别名
- NRAS antibody, AV095280 antibody, N-ras antibody, ALPS4 antibody, NRAS1 antibody, NS6 antibody, N-RAS antibody, fj99a10 antibody, wu:fj99a10 antibody, zgc:100761 antibody, zras-b1 antibody, H-RAS antibody, HRAS antibody, GTPase NRas antibody, neuroblastoma RAS viral (v-ras) oncogene homolog L homeolog antibody, NRAS proto-oncogene, GTPase antibody, neuroblastoma ras oncogene antibody, neuroblastoma RAS viral oncogene homolog antibody, Tsp_01117 antibody, nras.L antibody, Nras antibody, NRAS antibody, nras antibody
- 背景
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This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.
Alias Symbols: ALPS4, N-ras, NRAS1, NS6
Protein Interaction Partner: UBC, MDM2, RGL2, VAT1, RNASEH2B, SPATS2, CD2AP, ELAVL1, SRI, RPS20, DNAJB1, EEF1A1, RAP1GDS1, RASGRP2, PLCE1, SMURF2, RASSF5, RACGAP1, SHOC2, SMAD4, ARHGAP4, PIK3CA, RAF1, BCL2, ACVR1, PIK3CG, MLLT4,
Protein Size: 189 - 分子量
- 21 kDa
- 基因ID
- 4893
- NCBI登录号
- NM_002524, NP_002515
- UniProt
- P01111
- 途径
- p53 Pathway, MAPK Pathway, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
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