CD86 抗体 (C-Term)
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- 抗原 See all CD86 抗体
- CD86
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抗原表位
- C-Term
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适用
- 人, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CD86 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- WKKKKRPRNS YKCGTNTMER EESEQTKKRE KIHIPERSDE AQRVFKSSKT
- 预测反应
- Human: 100%, Pig: 92%
- 产品特性
- This is a rabbit polyclonal antibody against CD86. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product CD86 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 217 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- CD86
- 别名
- CD86 (CD86 产品)
- 别名
- B7-2 antibody, B7.2 antibody, B70 antibody, CD28LG2 antibody, LAB72 antibody, B7 antibody, CLS1 antibody, Cd28l2 antibody, ETC-1 antibody, Ly-58 antibody, Ly58 antibody, MB7 antibody, MB7-2 antibody, TS/A-2 antibody, CD86 molecule antibody, CD86 antigen antibody, integrin subunit alpha 2b antibody, CD86 antibody, Cd86 antibody, Itga2b antibody
- 背景
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This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.
Alias Symbols: B7-2, B70, CD28LG2, LAB72, MGC34413, B7.2
Protein Interaction Partner: UBC, CTLA4, ECE2, PARP1, MARCH1, MARCH8, CD86, CD28, CD80,
Protein Size: 217 - 分子量
- 23 kDa
- 基因ID
- 942
- NCBI登录号
- NM_175862, NP_787058
- UniProt
- E9PC27
- 途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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