FPGT 抗体 (C-Term)
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- 抗原 See all FPGT 抗体
- FPGT (Fucose-1-Phosphate Guanylyltransferase (FPGT))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 豚鼠, Cow, 犬, Pig, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FPGT antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- TSLNVVVLNN SKFYHIGTTE EYLFYFTSDN SLKSELGLQS ITFSIFPDIP
- 预测反应
- Cow: 86%, Dog: 86%, Guinea Pig: 86%, Human: 100%, Mouse: 79%, Pig: 100%, Rat: 79%
- 产品特性
- This is a rabbit polyclonal antibody against FPGT. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human FPGT
- Top Product
- Discover our top product FPGT Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 594 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- FPGT (Fucose-1-Phosphate Guanylyltransferase (FPGT))
- 别名
- FPGT (FPGT 产品)
- 背景
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L-fucose is a key sugar in glycoproteins and other complex carbohydrates since it may be involved in many of the functional roles of these macromolecules, such as in cell-cell recognition. The fucosyl donor for these fucosylated oligosaccharides is GDP-beta-L-fucose. There are two alternate pathways for the biosynthesis of GDP-fucose, the major pathway converts GDP-alpha-D-mannose to GDP-beta-L-fucose. The protein encoded by this gene participates in an alternate pathway that is present in certain mammalian tissues, such as liver and kidney, and appears to function as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids. This pathway involves the phosphorylation of L-fucose to form beta-L-fucose-1-phosphate, and then condensation of the beta-L-fucose-1-phosphate with GTP by fucose-1-phosphate guanylyltransferase to form GDP-beta-L-fucose. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream TNNI3 interacting kinase (TNNI3K) gene.
Alias Symbols: GFPP
Protein Interaction Partner: NLN,
Protein Size: 594 - 分子量
- 66 kDa
- 基因ID
- 8790
- NCBI登录号
- NM_003838, NP_003829
- UniProt
- O14772
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