CTPS2 抗体 (N-Term)
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- 抗原 See all CTPS2 抗体
- CTPS2 (CTP Synthase II (CTPS2))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 犬, 马, Cow, Pig, 兔, 斑马鱼, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CTPS2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- AKRENFCNIH VSLVPQLSAT GEQKTKPTQN SVRALRGLGL SPDLIVCRSS
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against CTPS2. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product CTPS2 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 586 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- CTPS2 (CTP Synthase II (CTPS2))
- 别名
- CTPS2 (CTPS2 产品)
- 别名
- A830031M15Rik antibody, AI326475 antibody, Ctpsh antibody, CTP synthase 2 L homeolog antibody, CTP synthase 2 antibody, cytidine 5'-triphosphate synthase 2 antibody, ctps2.L antibody, CTPS2 antibody, ctps2 antibody, Ctps2 antibody
- 背景
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The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Three alternatively spliced transcript variants encoding the same protein have been described for this gene.
Alias Symbols: DKFZp686C17207, FLJ43358, MGC32997
Protein Interaction Partner: CTPS2, SPG21, RNF2, LRSAM1, EHD4, EHD1, PLIN3, MTMR2, WARS, PRKDC, NUCB1, METTL1, KTN1, HSF1, GTF2I, DHPS, RPL37A, RPL23A, FGFR1, CTBP2, UBC, SUMO2, OTUD5,
Protein Size: 586 - 分子量
- 64 kDa
- 基因ID
- 56474
- NCBI登录号
- NM_175859, NP_787055
- UniProt
- Q9NRF8
- 途径
- Ribonucleoside Biosynthetic Process
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