Cyclin-Dependent Kinase 11A (CDK11A) (C-Term) 抗体
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- 抗原 See all Cyclin-Dependent Kinase 11A (CDK11A) 抗体
- Cyclin-Dependent Kinase 11A (CDK11A)
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抗原表位
- C-Term
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适用
- 人, 小鼠, 犬, 大鼠, Cow, 马, 兔, 豚鼠, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- 非结合性
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应用范围
- Western Blotting (WB)
- 序列
- EYFRETPLPI DPSMFPTWPA KSEQQRVKRG TSPRPPEGGL GYSQLGDDDL
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against CDK11A. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product CDK11A Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 767 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- Cyclin-Dependent Kinase 11A (CDK11A)
- 别名
- CDK11A (CDK11A 产品)
- 别名
- CDC2L2 antibody, CDC2L3 antibody, CDK11-p110 antibody, CDK11-p46 antibody, CDK11-p58 antibody, PITSLRE antibody, p58GTA antibody, CDC2L1 antibody, cPITSLRE antibody, cyclin dependent kinase 11A antibody, cyclin-dependent kinase 11A antibody, CDK11A antibody, LOC100338292 antibody
- 背景
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This gene encodes a member of the p34Cdc2 protein kinase family. p34Cdc2 kinase family members are known to be essential for eukaryotic cell cycle control. This gene is in close proximity to CDC2L1, a nearly identical gene in the same chromosomal region. The gene loci including this gene, CDC2L1, as well as metalloprotease MMP21/22, consist of two identical, tandemly linked genomic regions, which are thought to be a part of the larger region that has been duplicated. This gene and CDC2L1 were shown to be deleted or altered frequently in neuroblastoma with amplified MYCN genes. The protein kinase encoded by this gene could be cleaved by caspases and was demonstrated to play roles in cell apoptosis. Many transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of only two have been determined so far.
Alias Symbols: CDC2L2, CDC2L3, p58GTA, PITSLRE, CDK11-p46, CDK11-p58, CDK11-p110
Protein Interaction Partner: UBC, CDC37, FKBP5, PIN1, CDK11A, HKR1, C18orf25, RBM25, ZFP14, PRPF40A, NOP58, ZNF510, ZNF460, ZNF267, ZNF33A, PSMD1, KPNA2, KPNB1, CSNK2B, CSNK2A2, CSNK2A1, CDKN2A, A2M, SOX2, Dlg4, GADD45A, HSP90AA1, SMAD3, SUMO2, CCNL1, SRSF7, RNPS1, KAT7, PAK1, CASP8,
Protein Size: 767 - 分子量
- 84 kDa
- 基因ID
- 728642
- NCBI登录号
- NM_033529, NP_277071
- UniProt
- Q9UQ88
- 途径
- M Phase
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