cd36l2 antibody, fi13c07 antibody, chunp6914 antibody, wu:fi13c07 antibody, SCARB2 antibody, scarb2 antibody, AMRF antibody, CD36L2 antibody, EPM4 antibody, HLGP85 antibody, LGP85 antibody, LIMP-2 antibody, LIMPII antibody, SR-BII antibody, 9330185J12Rik antibody, Cd36l2 antibody, MLGP85 antibody, LimpII antibody, scavenger receptor class B, member 2a antibody, scavenger receptor class B member 2 antibody, scavenger receptor class B, member 2 antibody, scarb2a antibody, SCARB2 antibody, scarb2 antibody, Scarb2 antibody
背景
The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alias Symbols: AMRF, CD36L2, EPM4, HLGP85, LGP85, LIMP-2, LIMPII, SR-BII Protein Interaction Partner: UBC, ATP4A, TAF15, NONO, HSPD1, DDX1, ATP6V1B1, Ap1g1, AP3S2, AP3S1, THBS1, Protein Size: 478