Histone H3.3 抗体 (N-Term)
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- 抗原 See all Histone H3.3 (H3F3A) 抗体
- Histone H3.3 (H3F3A) (H3 Histone, Family 3A (H3F3A))
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抗原表位
- N-Term
- 适用
- 大鼠, 犬, Pig, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Histone H3.3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- KSAPSTGGVK KPHRYRPGTV ALREIRRYQK STELLIRKLP FQRLVREIAQ
- 预测反应
- Dog: 100%, Pig: 100%, Rat: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against H3f3a. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product H3F3A Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 126 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- Histone H3.3 (H3F3A) (H3 Histone, Family 3A (H3F3A))
- 别名
- H3f3a (H3F3A 产品)
- 别名
- H3.3A antibody, H3F3 antibody, h3f3a antibody, MGC52829 antibody, wu:fb58e10 antibody, zgc:56193 antibody, zgc:86731 antibody, H3-I antibody, H3-II antibody, H3-III antibody, H3-IV antibody, H3-V antibody, H3-VI antibody, H3-VII antibody, H3-VIII antibody, H3F3A antibody, h3.3 antibody, h3.3a antibody, CG5825 antibody, Dmel\\CG5825 antibody, H3.3 antibody, His-3.3A antibody, His3.3 antibody, PH3 antibody, dH3.3A antibody, H3 histone family member 3A antibody, H3 histone, family 3A antibody, H3 histone, family 3A L homeolog antibody, H3 histone, family 3C antibody, histone H3.3 antibody, histone cluster 1, H3a antibody, Histone H3.3A antibody, H3F3A antibody, h3f3a.L antibody, h3f3a antibody, H3F3C antibody, LOC475916 antibody, LOC480110 antibody, HIST1H3A antibody, LOAG_05159 antibody, His3.3A antibody, H3f3a antibody
- 背景
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H3f3a is a variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. H3f3a constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. H3f3a is deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Alias Symbols: H3.3A, H3f3b, MGC102150
Protein Interaction Partner: Kmt2d, Chd5, Setd1a, Kmt2c, Setd1b, Ezh2, Chd1, Cbx3, Uhrf1, Nfkb2, Hdac5, Hdac3, Kdm6b, Nfe2, Aurka, Cbx2, Ehmt2, Cbx5, Aurkb, Cbx6, Bptf, Creb3l4, Ing2, Cbx7, Cbx8, Cbx4, Cd4, Fosb, Rps6ka5, Rps6ka3, Igh-8, Cd79a, Tcrb, Eif2s3x, Kdm5c, Nanog, Kcnq1ot1,
Protein Size: 126 - 分子量
- 15 kDa
- 基因ID
- 15078
- NCBI登录号
- NM_008210, NP_032236
- UniProt
- P84244
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