PYM 抗体 (C-Term)
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- 抗原 See all PYM (WIBG) 抗体
- PYM (WIBG) (Partner of Y14 and mago (WIBG))
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抗原表位
- C-Term
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适用
- 人, 小鼠, Cow, 犬, 马, 豚鼠, 兔, 大鼠, Saccharomyces cerevisiae, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PYM antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- KKIKNLKKKL RQVEELQQRI QAGEVSQPSK EQLEKLARRR ALEEELEDLE
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 100%, Yeast: 100%
- 产品特性
- This is a rabbit polyclonal antibody against WIBG. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human WIBG
- Top Product
- Discover our top product WIBG Primary Antibody
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anti-Partner of Y14 and mago (WIBG) (AA 81-130) antibody
WIBG 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Partner of Y14 and mago (WIBG) (C-Term) antibodyWIBG 适用: 人, Cow, 犬, 马, Pig, Bat, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Partner of Y14 and mago (WIBG) antibodyWIBG 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Partner of Y14 and mago (WIBG) (AA 12-40), (N-Term) antibodyWIBG 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB28144 unconjugated
anti-Partner of Y14 and mago (WIBG) (AA 15-44), (N-Term) antibodyWIBG 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 204 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PYM (WIBG) (Partner of Y14 and mago (WIBG))
- 别名
- WIBG (WIBG 产品)
- 别名
- BEST:HL05757 antibody, CG10330 antibody, CG30176 antibody, Dmel\\CG30176 antibody, PYM antibody, Pym antibody, UD3 antibody, A030010B05Rik antibody, zgc:65891 antibody, zgc:77281 antibody, Partner of Y14 and Mago antibody, Wibg protein antibody, PYM homolog 1, exon junction complex associated factor L homeolog antibody, PYM homolog 1, exon junction complex associated factor antibody, Pym antibody, wibg antibody, pym1.L antibody, PYM1 antibody, Pym1 antibody, pym1 antibody
- 背景
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WIBG is a key regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmarks for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation. It acts as a EJC disassembly factor, allowing translation-dependent EJC removal and recycling by disrupting mature EJC from spliced mRNAs. Its association with the 40S ribosomal subunit probably prevents a translation-independent disassembly of the EJC from spliced mRNAs, by restricting its activity to mRNAs that have been translated. It interferes with NMD and enhances translation of spliced mRNAs, probably by antagonizing EJC functions.
Alias Symbols: MGC13064, PYM
Protein Interaction Partner: RTN4IP1, UBC, RPS19, RPS14, RPS13, RPS12, RPS10, RPS9, RPS8, RPS7, RPS6, RPS5, RPS4X, RPS3A, RPS3, RPS2, FAU, BYSL, ZNF503, PNO1, KCMF1, TSR1, RPS27L, UBQLN1, RPS29, RPS28, RPS27, RPS26, RPS25, RPS24, RPS23, RPS20, RPS18, RPS16, RPS15A, TARDBP, MAGOH, TOE
Protein Size: 204 - 分子量
- 23 kDa
- 基因ID
- 84305
- NCBI登录号
- NM_032345, NP_115721
- UniProt
- Q9BRP8
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