TCHP 抗体 (C-Term)
(1 reference)-
- 抗原 See all TCHP 抗体
- TCHP (Trichoplein, Keratin Filament Binding (TCHP))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马, Saccharomyces cerevisiae
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TCHP antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- IQEKIEQNRR AQEESLKHRE QLIRNLEEVR ELARREKEES EKLKSARKQE
- 预测反应
- Cow: 100%, Dog: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Yeast: 91%
- 产品特性
- This is a rabbit polyclonal antibody against TCHP. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human TCHP
- Top Product
- Discover our top product TCHP Primary Antibody
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anti-Trichoplein, Keratin Filament Binding (TCHP) (AA 1-498) antibody
TCHP 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Trichoplein, Keratin Filament Binding (TCHP) (C-Term) antibodyTCHP 适用: 人 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Trichoplein, Keratin Filament Binding (TCHP) (AA 291-320) antibodyTCHP 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB24714 unconjugated
anti-Trichoplein, Keratin Filament Binding (TCHP) (AA 306-370), (Middle Region) antibodyTCHP 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Trichoplein, Keratin Filament Binding (TCHP) (AA 387-436) antibodyTCHP 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马, 猴, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Trichoplein, Keratin Filament Binding (TCHP) (C-Term) antibodyTCHP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 498 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Embryonic Stem Cells Exhibit mRNA Isoform Specific Translational Regulation." in: PLoS ONE, Vol. 11, Issue 1, pp. e0143235, (2016) (PubMed).
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: "Embryonic Stem Cells Exhibit mRNA Isoform Specific Translational Regulation." in: PLoS ONE, Vol. 11, Issue 1, pp. e0143235, (2016) (PubMed).
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- 抗原
- TCHP (Trichoplein, Keratin Filament Binding (TCHP))
- 别名
- TCHP (TCHP 产品)
- 别名
- TpMs antibody, A930031F18Rik antibody, AV279199 antibody, RGD1310813 antibody, zgc:136634 antibody, trichoplein keratin filament binding antibody, trichoplein, keratin filament binding antibody, trichoplein, keratin filament binding L homeolog antibody, TCHP antibody, tchp antibody, Tchp antibody, tchp.L antibody
- 背景
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TCHP is a tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. It inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. It may act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. And it also may regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells.
Alias Symbols: MGC10854, TpMs
Protein Interaction Partner: CCDC172, MIPOL1, DYDC1, KRT40, LZTS2, NME7, NDOR1, MKRN3, TRIM27, NAB2, KRT15, CDR2, UBC, LATS2, CUL4A, CCDC85B, TEX11, VIM, KRT18, KRT16, KRT14, KRT8, KRT6A, KRT5,
Protein Size: 498 - 分子量
- 61 kDa
- 基因ID
- 84260
- NCBI登录号
- NM_032300, NP_115676
- UniProt
- Q9BT92
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