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AKR1C1 抗体 (N-Term)

DDH 适用: 人, 大鼠, 兔, Cow, 犬, 马, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2788358
发货至: 中国
  • 抗原 See all AKR1C1 (DDH) 抗体
    AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))
    抗原表位
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 36
    • 10
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 兔, Cow, 犬, 马, Pig
    宿主
    • 29
    • 7
    克隆类型
    • 32
    • 4
    多克隆
    标记
    • 25
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AKR1C1 antibody is un-conjugated
    应用范围
    • 23
    • 12
    • 11
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    LERSLKNLQL DYVDLYLIHF PVSVKPGEEV IPKDENGKIL FDTVDLCATW
    预测反应
    Cow: 86%, Dog: 77%, Horse: 77%, Human: 100%, Pig: 77%, Rabbit: 82%, Rat: 82%
    产品特性
    This is a rabbit polyclonal antibody against AKR1C1. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human AKR1C1
    Top Product
    Discover our top product DDH Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 323 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))
    别名
    AKR1C1 (DDH 产品)
    别名
    2-ALPHA-HSD antibody, 20-ALPHA-HSD antibody, C9 antibody, DD1 antibody, DD1/DD2 antibody, DDH antibody, DDH1 antibody, H-37 antibody, HAKRC antibody, HBAB antibody, MBAB antibody, aldo-keto reductase family 1 member C1 antibody, aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) antibody, AKR1C1 antibody
    背景
    This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
    Alias Symbols: 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DDH, DDH1, H-37, HAKRC, MBAB, MGC8954, HBAB, DD1/DD2
    Protein Interaction Partner: PTPN3, UBC, FN1, COMMD8, MAPK3, AKR1C1,
    Protein Size: 323
    分子量
    36 kDa
    基因ID
    1645
    NCBI登录号
    NM_001353, NP_001344
    UniProt
    Q04828
    途径
    Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
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