AKR1C1 抗体 (N-Term)
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- 抗原 See all AKR1C1 (DDH) 抗体
- AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))
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抗原表位
- N-Term
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适用
- 人, 大鼠, 兔, Cow, 犬, 马, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This AKR1C1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- LERSLKNLQL DYVDLYLIHF PVSVKPGEEV IPKDENGKIL FDTVDLCATW
- 预测反应
- Cow: 86%, Dog: 77%, Horse: 77%, Human: 100%, Pig: 77%, Rabbit: 82%, Rat: 82%
- 产品特性
- This is a rabbit polyclonal antibody against AKR1C1. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human AKR1C1
- Top Product
- Discover our top product DDH Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 323 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))
- 别名
- AKR1C1 (DDH 产品)
- 别名
- 2-ALPHA-HSD antibody, 20-ALPHA-HSD antibody, C9 antibody, DD1 antibody, DD1/DD2 antibody, DDH antibody, DDH1 antibody, H-37 antibody, HAKRC antibody, HBAB antibody, MBAB antibody, aldo-keto reductase family 1 member C1 antibody, aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) antibody, AKR1C1 antibody
- 背景
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This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Alias Symbols: 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DDH, DDH1, H-37, HAKRC, MBAB, MGC8954, HBAB, DD1/DD2
Protein Interaction Partner: PTPN3, UBC, FN1, COMMD8, MAPK3, AKR1C1,
Protein Size: 323 - 分子量
- 36 kDa
- 基因ID
- 1645
- NCBI登录号
- NM_001353, NP_001344
- UniProt
- Q04828
- 途径
- Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
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