-
- 抗原 See all F2RL1 抗体
- F2RL1 (Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1))
-
抗原表位
- C-Term
-
适用
- 人, 大鼠, 犬, 豚鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This F2RL1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 序列
- VSHDFRDHAK NALLCRSVRT VKQMQVSLTS KKHSRKSSSY SSSSTTVKTS
- 预测反应
- Dog: 93%, Guinea Pig: 86%, Human: 100%, Rat: 86%
- 产品特性
- This is a rabbit polyclonal antibody against F2RL1. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product F2RL1 Primary Antibody
-
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 397 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
Toward drugs for protease-activated receptor 2 (PAR2)." in: Journal of medicinal chemistry, Vol. 56, Issue 19, pp. 7477-97, (2013) (PubMed).
: "
-
Toward drugs for protease-activated receptor 2 (PAR2)." in: Journal of medicinal chemistry, Vol. 56, Issue 19, pp. 7477-97, (2013) (PubMed).
-
- 抗原
- F2RL1 (Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1))
- 别名
- F2RL1 (F2RL1 产品)
- 别名
- par2 antibody, GPR11 antibody, PAR2 antibody, Gpcr11 antibody, PAR-2 antibody, Par2 antibody, Par-2 antibody, Proteinase-activated receptor 2 antibody, F2R like trypsin receptor 1 antibody, coagulation factor II (thrombin) receptor-like 1 antibody, par2 antibody, F2RL1 antibody, F2rl1 antibody
- 背景
-
Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83 % identical to the mouse receptor sequence.
Alias Symbols: GPR11, PAR2
Protein Interaction Partner: BIRC5, COPS5, UBC, Cbl, ST14, GPRASP1, PRTN3, F2, PLG, ELANE, CTSG, CAPN2, CAPN1,
Protein Size: 397 - 分子量
- 44 kDa
- 基因ID
- 2150
- NCBI登录号
- NM_005242, NP_005233
- UniProt
- P55085
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interactome
-