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Adenosine A3 Receptor 抗体 (C-Term)

ADORA3 适用: 人, Pig, Cow, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2788278
发货至: 中国
  • 抗原 See all Adenosine A3 Receptor (ADORA3) 抗体
    Adenosine A3 Receptor (ADORA3)
    抗原表位
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 30
    • 15
    • 8
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    人, Pig, Cow, 马, 兔
    宿主
    • 31
    • 1
    • 1
    克隆类型
    • 32
    • 1
    多克隆
    标记
    • 25
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Adenosine A3 Receptor antibody is un-conjugated
    应用范围
    • 19
    • 13
    • 9
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    RSCKAPKVVR KADRSRTSIL IICILITGLG IISVISHLTK RRRSQRNRRV
    预测反应
    Cow: 75%, Horse: 93%, Human: 100%, Pig: 85%, Rabbit: 77%
    产品特性
    This is a rabbit polyclonal antibody against ADORA3. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human ADORA3
    Top Product
    Discover our top product ADORA3 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 266 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Merighi, Benini, Mirandola, Gessi, Varani, Leung, Maclennan, Baraldi, Borea: "Hypoxia inhibits paclitaxel-induced apoptosis through adenosine-mediated phosphorylation of bad in glioblastoma cells." in: Molecular pharmacology, Vol. 72, Issue 1, pp. 162-72, (2007) (PubMed).

  • 抗原
    Adenosine A3 Receptor (ADORA3)
    别名
    ADORA3 (ADORA3 产品)
    别名
    A3AR antibody, AD026 antibody, bA552M11.5 antibody, ADORA3 antibody, 1700001D09Rik antibody, 4930578J19Rik antibody, A3R antibody, AA3R antibody, ARA3 antibody, Gpcr2 antibody, adenosine A3 receptor antibody, adenosine receptor A3 antibody, ADORA3 antibody, Adora3 antibody, LOC100603318 antibody
    背景
    This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Multiple transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: A3AR, AD026, bA552M11.5, RP11-552M11.7
    Protein Interaction Partner: YWHAQ, YWHAZ,
    Protein Size: 266
    分子量
    30 kDa
    基因ID
    140
    NCBI登录号
    NM_001081976, NP_001075445
    UniProt
    Q5QNY7
    途径
    Hormone Transport, cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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