MRGPRX2 抗体 (Middle Region)
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- 抗原 See all MRGPRX2 抗体
- MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))
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抗原表位
- Middle Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MRGPRX2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- VCVLLWALSL LLSILEGKFC GFLFSDGDSG WCQTFDFITA AWLIFLFMVL
- 预测反应
- Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against MRGPRX2. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human MRGPRX2
- Top Product
- Discover our top product MRGPRX2 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 330 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))
- 别名
- MRGPRX2 (MRGPRX2 产品)
- 别名
- MRGX2 antibody, G370024M05Rik antibody, MrgB10 antibody, Mrgprb10 antibody, MrgB1 antibody, Mrgprb1 antibody, MAS related GPR family member X2 antibody, MAS-related GPR, member X2 antibody, MRGPRX2 antibody, Mrgprx2 antibody
- 背景
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MRGPRX2 is an orphan receptor. It probably involved in the function of nociceptive neurons. It also may regulate nociceptor function and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases in intracellular Ca2+ but had no effect on basal or forskolin-stimulated cAMP levels, suggesting that this receptor is G(q)-coupled.
Alias Symbols: MRGX2
Protein Interaction Partner: CORT,
Protein Size: 330 - 分子量
- 37 kDa
- 基因ID
- 117194
- NCBI登录号
- NM_054030, NP_473371
- UniProt
- Q96LB1
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