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CRY1 抗体 (N-Term)

CRY1 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 马, 绵羊, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2788200
发货至: 中国
  • 抗原 See all CRY1 抗体
    CRY1 (Cryptochrome 1 (Photolyase-Like) (CRY1))
    抗原表位
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 42
    • 19
    • 17
    • 15
    • 14
    • 14
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 兔, 马, 绵羊, 豚鼠, 斑马鱼
    宿主
    • 38
    • 6
    • 1
    克隆类型
    • 41
    • 4
    多克隆
    标记
    • 28
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CRY1 antibody is un-conjugated
    应用范围
    • 44
    • 18
    • 17
    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    KRFQTLISKM EPLEIPVETI TSEVIEKCTT PLSDDHDEKY GVPSLEELGF
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 93%
    产品特性
    This is a rabbit polyclonal antibody against CRY1. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human CRY1
    Top Product
    Discover our top product CRY1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 586 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Currie, Doherty, Sillar: "Deep-brain photoreception links luminance detection to motor output in Xenopus frog tadpoles." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 21, pp. 6053-8, (2016) (PubMed).

  • 抗原
    CRY1 (Cryptochrome 1 (Photolyase-Like) (CRY1))
    别名
    CRY1 (CRY1 产品)
    别名
    cry1-A antibody, CRY1 antibody, cry2 antibody, phll1 antibody, xCRY1 antibody, PHLL1 antibody, AU020726 antibody, AU021000 antibody, Phll1 antibody, ATCRY1 antibody, BLU1 antibody, BLUE LIGHT UNINHIBITED 1 antibody, CRYPTOCHROME 1 APOPROTEIN (BLUE LIGHT PHOTORECEPTOR antibody, ELONGATED HYPOCOTYL 4 antibody, HY4 antibody, OOP2 antibody, OUT OF PHASE 2 antibody, T3H13.14 antibody, T3H13_14 antibody, cryptochrome 1 antibody, cryptochrome circadian clock 1 L homeolog antibody, cryptochrome circadian regulator 1 antibody, cryptochrome circadian clock 1 antibody, Cryptochrome-1 antibody, cryptochrome 1 antibody, cryptochrome 1 (photolyase-like) antibody, cry1.L antibody, CRY1 antibody, cry1 antibody, siu50817b antibody, Cry1 antibody
    背景
    CRY1 is the blue light-dependent regulator of the circadian feedback loop. CRY1 inhibits CLOCK NPAS2-ARNTL E box-mediated transcription. CRY1 acts, in conjunction with CRY2, in maintaining period length and circadian rhythmicity. CRY1 has no photolyase activity. CRY1 is capable of translocating circadian clock core proteins such as PER proteins to the nucleus. CRY1 may inhibit CLOCK NPAS2-ARNTL transcriptional activity through stabilizing the unphosphorylated form of ARNTL.
    Alias Symbols: PHLL1
    Protein Interaction Partner: PER2, FBXL3, FBXL21, PLSCR1, BTRC, CUL1, SKP1, CSNK1E, LTBP4, UBC, SNRPD3, GRN, USP2, Timeless, Cry1, KRTAP4-12, PER3, MDFI, CBLB, ARNTL, PER1, TRAF2,
    Protein Size: 586
    分子量
    64 kDa
    基因ID
    1407
    NCBI登录号
    NM_004075, NP_004066
    UniProt
    Q16526
    途径
    Response to Water Deprivation, Proton Transport
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