RASSF1 抗体 (C-Term)
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- 抗原 See all RASSF1 抗体
- RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
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抗原表位
- C-Term
- 适用
- 人, 小鼠, 大鼠, Cow, 马, Pig, 犬, 绵羊, 斑马鱼, 豚鼠, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RASSF1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- LAGPSDKALS FVLKENDSGE VNWDAFSMPE LHNFLRILQR EEEEHLRQIL
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 85%
- 产品特性
- This is a rabbit polyclonal antibody against RASSF1. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human RASSF1
- Top Product
- Discover our top product RASSF1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 270 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
- 别名
- RASSF1 (RASSF1 产品)
- 别名
- RASSF1 antibody, zgc:92505 antibody, wu:fc17f02 antibody, zgc:112224 antibody, 123F2 antibody, NORE2A antibody, RASSF1A antibody, RDA32 antibody, REH3P21 antibody, AA536941 antibody, AU044980 antibody, Rassf1A antibody, Rassf1B antibody, Rassf1C antibody, NPR2-like, GATOR1 complex subunit antibody, Ras association (RalGDS/AF-6) domain family 1 antibody, Ras association domain family member 1 antibody, putative rassf1 antibody, Ras association domain family member 1 L homeolog antibody, Ras association (RalGDS/AF-6) domain family member 1 antibody, NPRL2 antibody, rassf1 antibody, RASSF1 antibody, Smp_157340 antibody, rassf1.L antibody, Rassf1 antibody
- 背景
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This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Alias Symbols: 123F2, NORE2A, RASSF1A, RDA32, REH3P21
Protein Interaction Partner: FBXW11, MDM2, DAXX, SUV39H2, KDM1A, SUV39H1, STK4, STK3, CDC20, SAV1, MAST2, HUWE1, LATS1, BTRC, UBC, ID1, GSK3B, C7orf25, C8orf33, KCNE3, CUL4A, DDB1, Rassf1, SKP2, AURKB, AURKA, SKP1, CUL1, NUDT10, MOAP1, CNKSR1, MAP1S, EXOSC8, RASSF5, TNFRSF10A, E4F1,
Protein Size: 270 - 分子量
- 30 kDa
- 基因ID
- 11186
- NCBI登录号
- NM_170713, NP_733831
- UniProt
- Q9NS23
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