GRM7 抗体 (C-Term)
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- 抗原 See all GRM7 抗体
- GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))
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抗原表位
- C-Term
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适用
- 人, 大鼠, 小鼠, 犬, 兔, Cow, 马, 斑马鱼, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GRM7 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- HPELNVQKRK RSFKAVVTAA TMSSRLSHKP SDRPNGEAKT ELCENVDPNS
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against GRM7. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human GRM7
- Top Product
- Discover our top product GRM7 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 915 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))
- 别名
- GRM7 (GRM7 产品)
- 别名
- MGLUR7 antibody, GLUR7 antibody, GPRC1G antibody, MGLU7 antibody, 6330570A01Rik antibody, BB176677 antibody, C030018L03 antibody, E130018M02Rik antibody, Gpr1g antibody, Gprc1g antibody, mGluR7 antibody, glutamate metabotropic receptor 7 antibody, glutamate receptor, metabotropic 7 antibody, GRM7 antibody, Grm7 antibody
- 背景
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L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: FLJ40498, GLUR7, GPRC1G, MGLU7, MGLUR7
Protein Interaction Partner: UBC, PICK1, TUBA8, TUBA1B, TUBA1A, TUBA3C, GNAQ, GRIPAP1, FLNA, TUBA4A, CALM3, CALM1, PRKCA, GRIP1, SDCBP,
Protein Size: 915 - 分子量
- 99 kDa
- 基因ID
- 2917
- NCBI登录号
- NM_000844, NP_000835
- UniProt
- Q14831
- 途径
- Sensory Perception of Sound, cAMP Metabolic Process, Feeding Behaviour
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