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COCH 抗体 (N-Term)

COCH 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2788127
发货至: 中国
  • 抗原 See all COCH 抗体
    COCH (Cochlin (COCH))
    抗原表位
    • 10
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    N-Term
    适用
    • 48
    • 12
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, 兔, Cow, 犬, 豚鼠, 马
    宿主
    • 46
    • 2
    克隆类型
    • 48
    多克隆
    标记
    • 21
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This COCH antibody is un-conjugated
    应用范围
    • 37
    • 27
    • 16
    • 13
    • 3
    • 2
    • 2
    Western Blotting (WB)
    序列
    AHPPTGKRLK KTPEKKTGNK DCKADIAFLI DGSFNIGQRR FNLQKNFVGK
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against COCH. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human COCH
    Top Product
    Discover our top product COCH Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 550 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    COCH (Cochlin (COCH))
    别名
    COCH (COCH 产品)
    别名
    AW122937 antibody, Coch-5B2 antibody, D12H14S564E antibody, COCH-5B2 antibody, COCH5B2 antibody, DFNA9 antibody, cochlin antibody, Coch antibody, COCH antibody
    背景
    The protein encoded by this gene is highly conserved in human, mouse, and chicken, showing 94 % and 79 % amino acid identity of human to mouse and chicken sequences, respectively. Hybridization to this gene was detected in spindle-shaped cells located along nerve fibers between the auditory ganglion and sensory epithelium. These cells accompany neurites at the habenula perforata, the opening through which neurites extend to innervate hair cells. This and the pattern of expression of this gene in chicken inner ear paralleled the histologic findings of acidophilic deposits, consistent with mucopolysaccharide ground substance, in temporal bones from DFNA9 (autosomal dominant nonsyndromic sensorineural deafness 9) patients. Mutations that cause DFNA9 have been reported in this gene. Alternative splicing results in multiple transcript variants encoding the same protein. Additional splice variants encoding distinct isoforms have been described but their biological validities have not been demonstrated.
    Alias Symbols: COCH-5B2, COCH5B2, DFNA9
    Protein Interaction Partner: FBXO6,
    Protein Size: 550
    分子量
    57 kDa
    基因ID
    1690
    NCBI登录号
    NM_001135058, NP_001128530
    UniProt
    O43405
    途径
    Sensory Perception of Sound
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