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alpha KGDHC 抗体 (N-Term)

alphaKGDHC 适用: 人, 大鼠, 小鼠, Cow, 马, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2787780
发货至: 中国
  • 抗原 See all alpha KGDHC (alphaKGDHC) 抗体
    alpha KGDHC (alphaKGDHC) (alpha Ketoglutarate Dehydrogenase (alphaKGDHC))
    抗原表位
    • 8
    • 8
    • 6
    • 5
    • 3
    • 1
    • 1
    N-Term
    适用
    人, 大鼠, 小鼠, Cow, 马, 兔, 豚鼠
    宿主
    • 37
    • 1
    克隆类型
    • 37
    • 1
    多克隆
    标记
    • 15
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This alpha KGDHC antibody is un-conjugated
    应用范围
    • 27
    • 20
    • 19
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    MFHLRTCAAK LRPLTASQTV KTFSQNRPAA ARTFQQIRCY SAPVAAEPFL
    预测反应
    Cow: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%
    产品特性
    This is a rabbit polyclonal antibody against OGDH. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human OGDH
    Top Product
    Discover our top product alphaKGDHC Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 427 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    alpha KGDHC (alphaKGDHC) (alpha Ketoglutarate Dehydrogenase (alphaKGDHC))
    别名
    OGDH (alphaKGDHC 产品)
    别名
    AKGDH antibody, E1k antibody, OGDC antibody, 2210403E04Rik antibody, 2210412K19Rik antibody, AA409584 antibody, d1401 antibody, mKIAA4192 antibody, oxoglutarate dehydrogenase antibody, oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) antibody, OGDH antibody, Ogdh antibody
    背景
    The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO2. It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitocondrial matrix and uses thiamine pyrophosphate as a cofactor. A congential deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia.
    Alias Symbols: AKGDH, E1k, OGDC
    Protein Interaction Partner: MDM2, UBC, SUMO1, NEDD8, CPSF7, MRPL38, MRPL41, TSR1, MRPS2, MRPL15, MRPL13, SCFD1, PDHX, SSBP1, SUMO2, PDHB, PDHA1, DLST, DLAT, DHODH, ISG15, USP13, PLSCR1, DLD,
    Protein Size: 427
    分子量
    47 kDa
    基因ID
    4967
    NCBI登录号
    NM_001003941, NP_001003941
    UniProt
    Q96DD3
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