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FN3KRP 抗体 (N-Term)

FN3KRP 适用: 人, 小鼠, 大鼠, Cow, 兔, 斑马鱼, 犬, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2787771
发货至: 中国
  • 抗原 See all FN3KRP 抗体
    FN3KRP (Fructosamine 3 Kinase Related Protein (FN3KRP))
    抗原表位
    • 2
    • 2
    • 1
    N-Term
    适用
    人, 小鼠, 大鼠, Cow, 兔, 斑马鱼, 犬, 豚鼠, 马
    宿主
    • 15
    • 1
    克隆类型
    • 16
    多克隆
    标记
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FN3KRP antibody is un-conjugated
    应用范围
    • 8
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    MDPGDPAGDP AAGERHRMGR DPLLLLQALQ TLWSTRERKQ LREEAWRGFA
    预测反应
    Cow: 86%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 93%, Zebrafish: 79%
    产品特性
    This is a rabbit polyclonal antibody against FN3KRP. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human FN3KRP
    Top Product
    Discover our top product FN3KRP Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 309 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Szwergold, Manevich, Payne, Loomes: "Fructosamine-3-kinase-related-protein phosphorylates glucitolamines on the C-4 hydroxyl: novel substrate specificity of an enigmatic enzyme." in: Biochemical and biophysical research communications, Vol. 361, Issue 4, pp. 870-5, (2007) (PubMed).

  • 抗原
    FN3KRP (Fructosamine 3 Kinase Related Protein (FN3KRP))
    别名
    FN3KRP (FN3KRP 产品)
    别名
    FN3KL antibody, FN3K-RP antibody, fn3k antibody, fn3kl antibody, MGC145992 antibody, DKFZP469K211 antibody, RGD1304570 antibody, zgc:101634 antibody, fructosamine 3 kinase related protein antibody, fructosamine-3-kinase-related protein antibody, FN3KRP antibody, Fn3krp antibody, fn3krp antibody
    背景
    FN3KRP phosphorylates psicosamines and ribulosamines, but not fructosamines, on the third carbon of the sugar moiety. Protein-bound psicosamine 3-phosphates and ribulosamine 3-phosphates are unstable and decompose under physiological conditions. Thus phosphorylation leads to deglycation.FN3KRP and FN3K (MIM 608425) protect proteins from nonenzymatic glycation by phosphorylating the modified amino acid. This phosphorylation destabilizes the sugar-amine linkage and leads to spontaneous decomposition (Conner et al., 2004 [PubMed 15381090]).[supplied by OMIM].
    Alias Symbols: FLJ12171, FN3KL
    Protein Interaction Partner: APP, CUL3, CUL4B, UBC, USP43,
    Protein Size: 309
    分子量
    34 kDa
    基因ID
    79672
    NCBI登录号
    NM_024619, NP_078895
    UniProt
    Q9HA64
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