SOD2 抗体 (N-Term)
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- 抗原 See all SOD2 抗体
- SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))
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抗原表位
- N-Term
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适用
- 人, 大鼠, 小鼠, 绵羊, 犬, Cow, 豚鼠, 兔, 山羊, 马, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SOD2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- MLSRAVCGTS RQLAPVLGYL GSRQKHSLPD LPYDYGALEP HINAQIMQLH
- 预测反应
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%
- 产品特性
- This is a rabbit polyclonal antibody against SOD2. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human SOD2
- Top Product
- Discover our top product SOD2 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 222 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))
- 别名
- SOD2 (SOD2 产品)
- 背景
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SOD2 is a member of the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene encoding SOD2 have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer.This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: IPO-B, MNSOD, Mn-SOD, IPOB, MVCD6
Protein Interaction Partner: CYP4F12, UBC, SOD2, SOD1, APP, NABP2, TBL2, ZC3H11A, VAPA, STX7, UBL4A, ALDH5A1, USP36, H2AFX, SUMO1, NOL12, HDHD2, GET4, RPS3A, RAB4A, AURKA,
Protein Size: 222 - 分子量
- 24 kDa
- 基因ID
- 6648
- NCBI登录号
- NM_000636, NP_000627
- UniProt
- P04179
- 途径
- Sensory Perception of Sound, Transition Metal Ion Homeostasis, Negative Regulation of intrinsic apoptotic Signaling
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