GRB2 抗体 (N-Term)
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- 抗原 See all GRB2 抗体
- GRB2 (Growth Factor Receptor-Bound Protein 2 (GRB2))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 马, 兔, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GRB2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- AKYDFKATAD DELSFKRGDI LKVLNEECDQ NWYKAELNGK DGFIPKNYIE
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against GRB2. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product GRB2 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 217 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- GRB2 (Growth Factor Receptor-Bound Protein 2 (GRB2))
- 别名
- GRB2 (GRB2 产品)
- 别名
- GRB2 antibody, grb2 antibody, AA408164 antibody, Ash antibody, ASH antibody, EGFRBP-GRB2 antibody, Grb3-3 antibody, MST084 antibody, MSTP084 antibody, NCKAP2 antibody, wu:fb18e12 antibody, wu:fb34e06 antibody, zgc:73077 antibody, growth factor receptor bound protein 2 antibody, growth factor receptor-bound protein 2 antibody, growth factor receptor-bound protein 2b antibody, GRB2 antibody, grb2 antibody, Grb2 antibody, grb2b antibody
- 背景
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The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2
Protein Interaction Partner: AES, C1orf94, LNX1, LZTS2, GAREM, ARHGAP9, NIF3L1, HOMEZ, DPPA4, TP53BP2, SHC1, TRIM27, REL, EPS8, HNRNPK, ERBB4, ABI3, ZBTB7B, IKZF3, INCA1, PRR22, PNMA5, STAMBP, DDX17, CBLB, LMO2, LCP2, ABL2, ABL1, NUTM2F, WBP11, GAB2, WASL, UBC, CBL, DNM1, EGFR, ACTG1
Protein Size: 217 - 分子量
- 24 kDa
- 基因ID
- 2885
- NCBI登录号
- NM_002086, NP_002077
- UniProt
- P62993
- 途径
- RTK signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, EGFR Downregulation
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