Calpain S1 抗体 (Middle Region)
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- 抗原 See all Calpain S1 (CAPNS1) 抗体
- Calpain S1 (CAPNS1) (Calpain, Small Subunit 1 (CAPNS1))
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抗原表位
- Middle Region
- 适用
- 人, 小鼠, 大鼠, Cow, Pig, 兔, 犬, 豚鼠, 马, 绵羊
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Calpain S1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- RRYSDESGNM DFDNFISCLV RLDAMFRAFK SLDKDGTGQI QVNIQEWLQL
- 预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%
- 产品特性
- This is a rabbit polyclonal antibody against CAPNS1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human CAPNS1
- Top Product
- Discover our top product CAPNS1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 268 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Differential proteomic analysis of caveolin-1 KO cells reveals Sh2b3 and Clec12b as novel interaction partners of caveolin-1 and Capns1 as a potential mediator of caveolin-1-induced apoptosis." in: The Analyst, Vol. 138, Issue 22, pp. 6986-96, (2013) (PubMed).
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Differential proteomic analysis of caveolin-1 KO cells reveals Sh2b3 and Clec12b as novel interaction partners of caveolin-1 and Capns1 as a potential mediator of caveolin-1-induced apoptosis." in: The Analyst, Vol. 138, Issue 22, pp. 6986-96, (2013) (PubMed).
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- 抗原
- Calpain S1 (CAPNS1) (Calpain, Small Subunit 1 (CAPNS1))
- 别名
- CAPNS1 (CAPNS1 产品)
- 别名
- 30K antibody, CALPAIN4 antibody, CANP antibody, CANPS antibody, CAPN4 antibody, CDPS antibody, CSS1 antibody, Capn4 antibody, CAPNS1 antibody, Capa-4 antibody, Capa4 antibody, D7Ertd146e antibody, MGC84330 antibody, capns1 antibody, cb616 antibody, wu:fb81g08 antibody, wu:fl09e04 antibody, zgc:110603 antibody, calpain small subunit 1 antibody, calpain, small subunit 1 antibody, calpain, small subunit 1 L homeolog antibody, calpain, small subunit 1 a antibody, CAPNS1 antibody, Capns1 antibody, capns1.L antibody, capns1a antibody
- 背景
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Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene.
Alias Symbols: 30K, CALPAIN4, CANP, CANPS, CAPN4, CDPS, CSS1
Protein Interaction Partner: AGTRAP, HUWE1, NEDD1, TUBGCP2, TUBGCP3, CDC20, UBC, OGFOD1, STK26, ISOC1, DCPS, MAT2B, PROSC, FERMT2, YWHAQ, PDIA4, YWHAZ, YWHAH, YWHAG, YWHAE, PTMA, PPP1CA, PAK2, PAFAH1B1, MYO1E, MAT2A, GNAI3, GAPDH, EIF5, TBCB, ALDH7A1, ASNS, APEX1, ADRB2, PPARGC1A, VC
Protein Size: 268 - 分子量
- 29 kDa
- 基因ID
- 826
- NCBI登录号
- NM_001003962, NP_001003962
- UniProt
- P04632
- 途径
- Apoptosis
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